舍曲林与帕罗西汀在广泛性焦虑症患者中的疗效对比观察及对生活质量的影响研究
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摘要
目的研究舍曲林与帕罗西汀在广泛性焦虑症患者中的临床疗效,评价对生活质量的影响。方法方便选取该院2016年12月—2017年12月入院治疗的广泛性焦虑症患者100例,采用随机数字表法的形式将其平均分为实验组与对照组,每组均50例。实验组行舍曲林治疗法,对照组行帕罗西汀治疗法,对比分析两组临床疗效与治疗之后生活质量评分指标。结果实验组临床疗效为92.0%,对照组临床疗效为70.0%,实验组高于对照组,组间对比呈现为(P<0.05)的差异性。实验组生活质量评分为(56.2±1.1)分,对照组生活质量评分为(35.6±2.2)分,对照组低于实验组,组间比较差异有统计学意义(P<0.05)。结论在广泛性焦虑症患者临床治疗的过程中,采用舍曲林治疗法,能够帮助患者提升临床疗效,改善治疗之后的生活质量,值得进行推广。
Objective To evaluate the effect of sertraline and paroxetine on quality of life in patients with generalized anxiety disorder. Methods Convenient select 100 patients with generalized anxiety disorder who were admitted to hospital from December 2016 to December 2017 were randomly divided into experimental group and control group with 50 cases in each group. The experimental group was treated with sertraline and the control group with paroxetine. Results The clinical curative effect was 92.0% in the experimental group and 70.0% in the control group. The difference between the two groups was(P<0.05). The quality of life score was(56.2 ±1.1)points in the experimental group and(35.6±2.2)points in the control group, which was significantly lower than that in the experimental group,the difference was statistically significant(P<0.05).Conclusion In the course of clinical treatment of patients with generalized anxiety disorder, sertraline therapy can help patients to improve the clinical efficacy, improve the quality of life after treatment, and it is worth popularizing.
Objective To evaluate the effect of sertraline and paroxetine on quality of life in patients with generalized anxiety disorder. Methods Convenient select 100 patients with generalized anxiety disorder who were admitted to hospital from December 2016 to December 2017 were randomly divided into experimental group and control group with 50 cases in each group. The experimental group was treated with sertraline and the control group with paroxetine. Results The clinical curative effect was 92.0% in the experimental group and 70.0% in the control group. The difference between the two groups was(P<0.05). The quality of life score was(56.2 ±1.1)points in the experimental group and(35.6±2.2)points in the control group, which was significantly lower than that in the experimental group,the difference was statistically significant(P<0.05).Conclusion In the course of clinical treatment of patients with generalized anxiety disorder, sertraline therapy can help patients to improve the clinical efficacy, improve the quality of life after treatment, and it is worth popularizing.
引文
[1]刘建军.舍曲林与帕罗西汀治疗广泛性焦虑症临床疗效对比[J].中国现代药物应用,2017(17):145-146.
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[3]姚晓燕,刘军,李珊珊,等.针刺治疗广泛性焦虑症取穴规律研究[J].中国中医药信息杂志,2017(7):94-97.
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[7]邹晓君.舒适护理对广泛性焦虑症疗效的影响[J].国际护理学杂志,2016(21):2967-2969.
[8]徐维尧,韩金会.文拉法辛缓释片治疗广泛性焦虑症的临床疗效及安全性分析[J].中国实用神经疾病杂志,2017(10):117-119.
[2]张玮,李华南,赵娜,等.腹部推拿治疗广泛性焦虑症的随机对照研究[J].天津中医药大学学报,2017(6):441-444.
[3]姚晓燕,刘军,李珊珊,等.针刺治疗广泛性焦虑症取穴规律研究[J].中国中医药信息杂志,2017(7):94-97.
[4]张家宁,李文涛.广泛性焦虑症的中医认识及研究现状[J].中西医结合心脑血管病杂志,2016(12):1360-1363.
[5]孙志国,杨巍,冯萍萍,等.广泛性焦虑症患者血清神经递质及凝血相关指标的变化分析[J].中国实用神经疾病杂志,2016(16):36-37.
[6]巴义然.健身锻炼联合放松训练治疗广泛性焦虑症老年患者的疗效观察[J].中华物理医学与康复杂志,2018(4):309-310.
[7]邹晓君.舒适护理对广泛性焦虑症疗效的影响[J].国际护理学杂志,2016(21):2967-2969.
[8]徐维尧,韩金会.文拉法辛缓释片治疗广泛性焦虑症的临床疗效及安全性分析[J].中国实用神经疾病杂志,2017(10):117-119.