2010-2018年浙江省宁波市6-35月龄儿童季节性流感疫苗接种率分析
|
摘要
目的分析2010-2018年浙江省宁波市6-35月龄儿童季节性流感疫苗(SIV)接种率及其影响因素。方法利用宁波市免疫预防管理信息系统收集2010/2011-2017/2018年度6-35月龄儿童SIV接种信息,描述性分析1剂次SIV(SIV1)和2剂次SIV(SIV2)接种率,采用Logistic回归模型分析SIV2接种的影响因素。结果宁波市适龄儿童SIV1、SIV2接种率分别从2010/2011年度的7.41%、4.54%增长到2017/2018年度的8.06%、5.90%; SIV1、SIV2及时接种率分别从5.76%、2.63%增长到6.95%、4.07%。Logistic回归分析显示,儿童年龄、户籍、居住地区、门诊接种服务频次、周末提供服务和门诊接种人员配置是影响SIV2接种的主要因素。结论宁波市6-35月龄儿童SIV接种率较低。需要进一步提升接种门诊服务质量,提高儿童SIV接种率。
Objective To evaluate coverage of seasonal influenza vaccine(SIV) among 6-35 month olds in Ningbo city during 2010-2018. Methods We used the Ningbo Immunization Information System to collect SIV vaccination data of 6-35 month old children during 2010/2011-2017/2018 for an analysis of one-dose SIV(SIV1) and two-dose SIV(SIV2) coverage. We determined factors influencing SIV2 vaccination using logistic regression. Results SIV1 and SIV2 coverage increased from 7.41% and 4.54% in 2010/2011 to 8.06% and 5.90% in 2017/2018, with timely coverage increasing from 5.76% and 2.63% to 6.95% and 4.07%, respectively. Logistic regression showed that age, local/nonlocal residence, rural/urban area, vaccination session, weekend service, and staff number were significant factors influencing SIV2 coverage. Conclusions SIV coverage was low among children aged 6-35 months in Ningbo. We should improve vaccination services to increase SIV coverage in children.
Objective To evaluate coverage of seasonal influenza vaccine(SIV) among 6-35 month olds in Ningbo city during 2010-2018. Methods We used the Ningbo Immunization Information System to collect SIV vaccination data of 6-35 month old children during 2010/2011-2017/2018 for an analysis of one-dose SIV(SIV1) and two-dose SIV(SIV2) coverage. We determined factors influencing SIV2 vaccination using logistic regression. Results SIV1 and SIV2 coverage increased from 7.41% and 4.54% in 2010/2011 to 8.06% and 5.90% in 2017/2018, with timely coverage increasing from 5.76% and 2.63% to 6.95% and 4.07%, respectively. Logistic regression showed that age, local/nonlocal residence, rural/urban area, vaccination session, weekend service, and staff number were significant factors influencing SIV2 coverage. Conclusions SIV coverage was low among children aged 6-35 months in Ningbo. We should improve vaccination services to increase SIV coverage in children.
引文
[1]SONG X,XIAO J,DENG J,et al.Time series analysis ofinfluenza incidence in Chinese provinces from 2004 to2011[J].Medicine(Baltimore),2016,95(26):e3929.
[2]World Health Organization.Up to 650 000 people die ofrespiratory diseases linked to seasonal flu each year[EB/OL].2018-06.http://www.who.int/news-room/detail/14-12-2017-up-to-650-000-people-die-of-respiratory-diseaseslinkedto-seasonal-flu-each-year.
[3]WEBSTER RG,MONTO AS,BRACIALE TJ,et al.Text book ofinfluenza[M].Hboken:Wiley-Blackwell,2013.
[4]GUO RN,ZHENG HZ,HUANG LQ,et al.Epidemiologic and economic burden ofinfluenza in the outpat ient setting:a prospective study in a subtropical area ofChina[J].PLoS One,2012,7(7):e41403.
[5]GUO RN,ZHENG HZ,OU CQ,et al.Impact ofinfluenza on outpatient visits,hospitalizations,and deaths by using a time series Poisson generalized additive model[J].PLoSOne,2016,11(2):e149468.
[6]冯录召,杨鹏,张涛,等.中国季节性流感疫苗应用技术指南(2014-2015)[J].中华流行病学杂志,2014,35(12):1295-1319.FENG Luzhao,YANG Peng,ZHANG Tao,et al.Technical guidelines for the applicat ion ofseasonal influenza vaccine in China(2014-2015)[J].Chinese Journal ofEpidemiology,2014,35(12):1295-1319.
[7]World Health Organization.Vaccines against influenza.WHO position paper-November 2012(WHO,November 232012)[S].
[8]HU Y,CHEN Y,ZHANG B.Two-dose seasonal influenza vaccine coverage and timeliness among children aged 6months through 3 years:an evidence from the 2010-11 to the 2014-15 seasons in Zhejiang province,east China[J].Hum Vaccin Immunother,2017,13(1):75-80.
[9]叶莉霞,方挺,孙烨祥,等.宁波市成人预防接种门诊建设探讨[J].中国公共卫生管理,2018,34(1):67-70.YE Lixia,FANG Ting,SUN Yexiang,et al.Discussion on construction ofadult preventive outpatient clinic in Ningbo[J].Chinese Journal ofPublic Health Management,2018,34(1):67-70.
[10]国家药典委员会.中华人民共和国药典三部(2015版)[M].北京:中国医药科技出版社,2015.Chinese Pharmacopoeia Commission.Pharmacopoeia ofthe People's Republic ofChina,PartⅢ(Version 2015)[M].Bei jing:China Medical Science and Technology Publications,2015.
[11]劳旭影,焦素黎,纪威,等.宁波市流行性感冒相关超额死亡分析[J].预防医学,2016,28(10):1010-1013+1018.LAO Xuying,JIAO Suli,JI Wei,et al.An analysis on the influenza-related excess mortality in Ningbo city[J].Preventive Medicine,2016,28(10):1010-1013+1018.
[12]L IN X,F I EBE LKOR N AP,PABST L J.Trends in compliance with two-dosein fluenzavacc in e recommendations in children aged 6 months through 8years,2010-2015[J].Vaccine,2016,34(46):5623-5628.
[13]GENTILE A,JUAREZ M,HERNANDEZ S,e t a l.Influenza vaccine:delayed vaccination schedules and missed opportunities in children under 2 years old[J].Vaccine,2015,33(32):3913-3917.
[14]ZHOU L,SU Q,XU Z,e t a l.Sea sona l infl uen z a vaccination coverage rate oftarget groups in selected ci t ies and provinces in China by season(2009/10 to2011/12)[J].PLoS One,2013,8(9):e73724.
[15]段瑾.北京市朝阳区儿童家长第二类疫苗接种意愿及影响因素研究[D].北京:中国疾病预防控制中心,2017.DUAN Jin.A case study ofthe second category ofvaccination intention and influencing factors ofparents ofchildren in Chaoyang district[D].Beijing:Chinese Center for Disease Control and Prevention,2017.
[16]张雪海,孟强,陈士华,等.儿童家长对二类疫苗接受程度及影响因素分析[J].浙江预防医学,2016,28(4):336-339.ZHANG Xuehai,MENG Qiang,CHEN Shihua,et al.An analysis on parents'acceptance ofcharge vaccines and its influencing factors[J].Zhejiang Journal ofPreventive Medicine,2016,28(4):336-339.
[17]潘兴强,方挺,马瑞,等.宁波市本地儿童与流动儿童家长第二类疫苗预防接种知识调查[J].预防医学,2017,29(12):1284-1286.PANG Xingqiang,FANG Ting,MA Rui,et al.Investigation on local and migrant children's parents'knowledge on categoryⅡvaccine in Ningbo[J].Preventive Medicine,2017,29(12):1284-1286.
[2]World Health Organization.Up to 650 000 people die ofrespiratory diseases linked to seasonal flu each year[EB/OL].2018-06.http://www.who.int/news-room/detail/14-12-2017-up-to-650-000-people-die-of-respiratory-diseaseslinkedto-seasonal-flu-each-year.
[3]WEBSTER RG,MONTO AS,BRACIALE TJ,et al.Text book ofinfluenza[M].Hboken:Wiley-Blackwell,2013.
[4]GUO RN,ZHENG HZ,HUANG LQ,et al.Epidemiologic and economic burden ofinfluenza in the outpat ient setting:a prospective study in a subtropical area ofChina[J].PLoS One,2012,7(7):e41403.
[5]GUO RN,ZHENG HZ,OU CQ,et al.Impact ofinfluenza on outpatient visits,hospitalizations,and deaths by using a time series Poisson generalized additive model[J].PLoSOne,2016,11(2):e149468.
[6]冯录召,杨鹏,张涛,等.中国季节性流感疫苗应用技术指南(2014-2015)[J].中华流行病学杂志,2014,35(12):1295-1319.FENG Luzhao,YANG Peng,ZHANG Tao,et al.Technical guidelines for the applicat ion ofseasonal influenza vaccine in China(2014-2015)[J].Chinese Journal ofEpidemiology,2014,35(12):1295-1319.
[7]World Health Organization.Vaccines against influenza.WHO position paper-November 2012(WHO,November 232012)[S].
[8]HU Y,CHEN Y,ZHANG B.Two-dose seasonal influenza vaccine coverage and timeliness among children aged 6months through 3 years:an evidence from the 2010-11 to the 2014-15 seasons in Zhejiang province,east China[J].Hum Vaccin Immunother,2017,13(1):75-80.
[9]叶莉霞,方挺,孙烨祥,等.宁波市成人预防接种门诊建设探讨[J].中国公共卫生管理,2018,34(1):67-70.YE Lixia,FANG Ting,SUN Yexiang,et al.Discussion on construction ofadult preventive outpatient clinic in Ningbo[J].Chinese Journal ofPublic Health Management,2018,34(1):67-70.
[10]国家药典委员会.中华人民共和国药典三部(2015版)[M].北京:中国医药科技出版社,2015.Chinese Pharmacopoeia Commission.Pharmacopoeia ofthe People's Republic ofChina,PartⅢ(Version 2015)[M].Bei jing:China Medical Science and Technology Publications,2015.
[11]劳旭影,焦素黎,纪威,等.宁波市流行性感冒相关超额死亡分析[J].预防医学,2016,28(10):1010-1013+1018.LAO Xuying,JIAO Suli,JI Wei,et al.An analysis on the influenza-related excess mortality in Ningbo city[J].Preventive Medicine,2016,28(10):1010-1013+1018.
[12]L IN X,F I EBE LKOR N AP,PABST L J.Trends in compliance with two-dosein fluenzavacc in e recommendations in children aged 6 months through 8years,2010-2015[J].Vaccine,2016,34(46):5623-5628.
[13]GENTILE A,JUAREZ M,HERNANDEZ S,e t a l.Influenza vaccine:delayed vaccination schedules and missed opportunities in children under 2 years old[J].Vaccine,2015,33(32):3913-3917.
[14]ZHOU L,SU Q,XU Z,e t a l.Sea sona l infl uen z a vaccination coverage rate oftarget groups in selected ci t ies and provinces in China by season(2009/10 to2011/12)[J].PLoS One,2013,8(9):e73724.
[15]段瑾.北京市朝阳区儿童家长第二类疫苗接种意愿及影响因素研究[D].北京:中国疾病预防控制中心,2017.DUAN Jin.A case study ofthe second category ofvaccination intention and influencing factors ofparents ofchildren in Chaoyang district[D].Beijing:Chinese Center for Disease Control and Prevention,2017.
[16]张雪海,孟强,陈士华,等.儿童家长对二类疫苗接受程度及影响因素分析[J].浙江预防医学,2016,28(4):336-339.ZHANG Xuehai,MENG Qiang,CHEN Shihua,et al.An analysis on parents'acceptance ofcharge vaccines and its influencing factors[J].Zhejiang Journal ofPreventive Medicine,2016,28(4):336-339.
[17]潘兴强,方挺,马瑞,等.宁波市本地儿童与流动儿童家长第二类疫苗预防接种知识调查[J].预防医学,2017,29(12):1284-1286.PANG Xingqiang,FANG Ting,MA Rui,et al.Investigation on local and migrant children's parents'knowledge on categoryⅡvaccine in Ningbo[J].Preventive Medicine,2017,29(12):1284-1286.