岩盐气溶胶疗法对尘肺患者生活质量的影响
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摘要
目的了解岩盐气溶胶疗法对尘肺患者生活质量的影响。方法采用多中心随机对照临床试验,选取有代表性的6家单位于2016年11月—2017年4月收治的252例煤工尘肺病患者为调查对象,根据尘肺期别对入组患者进行分层,在每个层内按照随机的原则分为对照组和岩盐气溶胶治疗组(简称治疗组),对照组采取临床常规治疗,治疗组在常规治疗基础上加用岩盐气溶胶治疗,1次/日,1 h/次,共4周,分别在治疗前、治疗2周后、治疗4周后用自制尘肺患者生存质量评估表进行评价,并对数据进行分析。结果两组患者在治疗2周、4周后与治疗前比较,生活质量评分均有提高,差异有统计学意义(P<0.05);治疗组患者在治疗2周与4周后比较,生活质量评分差异有统计学意义(P<0.05);治疗后各时点、各期别患者生活质量评分改善程度,治疗组大于对照组,差异有统计学意义(P<0.05)。结论尘肺患者常规治疗基础上加用岩盐气溶胶疗法可以明显改善临床症状,提高生活质量,其效果优于单纯常规治疗。
[Objective]To investigate the effect of rock salt aerosol therapy on the quality of life of pneumoconiosis patients.[Methods]A multi-center randomized controlled trial was performed. A total of 254 patients with pneumoconiosis admitted to six representative units from November 2016 to April 2017 were selected as the subjects of investigation. The patients were stratified according to the stage of pneumoconiosis,and then were divided into the control group and the rock salt aerosol treatment group(the treatment group) according to the principle of randomization in each layer. The control group was treated with routine clinical treatment,while the treatment group was treated with rock salt aerosol on the basis of routine treatment,once a day,one hour at a time,for four weeks. The patients were evaluated by the self-made quality of life assessment table for pneumoconiosis patients before treatment,two weeks after treatment and four weeks after treatment,and the data were analyzed.[Results]The life quality scores of the two groups were improved after two weeks and four weeks of treatment,and the difference was statistically significant(P <0.05). The difference in life quality scores in the treatment was statistically significant between two weeks and four weeks of treatment(P<0.05). After the treatment,the improvement of life quality scores at each time point and each stage of patients in the treatment group was higher than that in the control group,and the difference was statistically significant(P<0.05).[Conclusion]The addition of rock salt aerosol therapy to routine treatment of pneumoconiosis patients can significantly improve clinical symptoms and improve quality of life,and its effect is better than routine treatment.
[Objective]To investigate the effect of rock salt aerosol therapy on the quality of life of pneumoconiosis patients.[Methods]A multi-center randomized controlled trial was performed. A total of 254 patients with pneumoconiosis admitted to six representative units from November 2016 to April 2017 were selected as the subjects of investigation. The patients were stratified according to the stage of pneumoconiosis,and then were divided into the control group and the rock salt aerosol treatment group(the treatment group) according to the principle of randomization in each layer. The control group was treated with routine clinical treatment,while the treatment group was treated with rock salt aerosol on the basis of routine treatment,once a day,one hour at a time,for four weeks. The patients were evaluated by the self-made quality of life assessment table for pneumoconiosis patients before treatment,two weeks after treatment and four weeks after treatment,and the data were analyzed.[Results]The life quality scores of the two groups were improved after two weeks and four weeks of treatment,and the difference was statistically significant(P <0.05). The difference in life quality scores in the treatment was statistically significant between two weeks and four weeks of treatment(P<0.05). After the treatment,the improvement of life quality scores at each time point and each stage of patients in the treatment group was higher than that in the control group,and the difference was statistically significant(P<0.05).[Conclusion]The addition of rock salt aerosol therapy to routine treatment of pneumoconiosis patients can significantly improve clinical symptoms and improve quality of life,and its effect is better than routine treatment.
引文
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[9]王洋,姜鹏,马丽丽,等.岩盐气溶胶疗法在尘肺病康复治疗中的临床疗效观察[J].大家健康,2014,8(11):134-135.
[10]崔桂华.岩盐气溶胶治疗硅肺的临床疗效观察[J].中国疗养医学,2017,26(10):1023-1025.
[11]熊政,张艳霞,焦深山.岩盐气溶胶疗法在支气管哮喘中临床疗效分析[J].中国医疗前沿,2013,8(17):27-28.
[12]李红艳,翁恒,王琳,等.岩盐气溶胶疗法治疗支气管哮喘患者的临床疗效及机制研究[J].中华结核和呼吸杂志,2013,36(6):460-461.
[13]方积乾,陆盈.现代统计学[M].北京:人民卫生出版社,2002:118.
[14]邱新香,陈慈珊,巫带花,等.尘肺患者心理状况及其生活质量研究进展[J].中国职业医学,2008,35(6):521-524.
[15]邱新香,郝元涛,梁智平,等.尘肺患者生活质量的相关因素研究[J].中国卫生统计,2011,28(3):233-236.
[16]田银君,刘前桂,李金红,等.多学科、综合性肺康复对老年尘肺患者的效果[J].中国康复医学,2017,23(3):352-357.
[17]苑云杰,苑树君,杨平,等.盐岩气溶胶疗法对老年肺尘埃沉着病患者疗效及生存质量的影响[J].中国老年学,2016,36(23):6015-6016.
[2]李智民,刘璐,张健杰.尘肺病的护理与康复[M].北京:人民卫生出版社,2017:17.
[3]张敏,王丹,郑迎东,等.中国1997至2009年报告尘肺病发病特征和变化趋势[J].中华劳动卫生职业病杂志,2013,31(5):321-334.
[4]徐英军,陈志远,于立群,等.接受肺灌洗的尘肺患者的生存质量及影响因素-尘肺并生存质量专用量表的应用[J].中国煤炭工业医学杂志,2014,17(10):1646-1649.
[5]中华人民共和国国家卫生和计划生育委员会.职业性尘肺病的诊断:GBZ 70-2015[S].北京:人民卫生出版社,2015:1-13.
[6]邹昌淇.积极治疗尘肺保护工人健康[J].中华劳动卫生职业病杂志,2011,29(8):561.
[7]谢文林,沈波.健康教育对尘肺患者生存质量影响的研究[J].中国现代医学,2014,52(1):112-115.
[8]GRIGOR EVA NV.Halotherapy in combined non-puncture tferapy of patients with acute purulent maxillary sinusitis[J/OL].Vestn Otornolaringol,2003(4):42-44.[2018-12-03].http//www.ncbi.nlm.nih.gov/pubmed/13677023.pmid:13677023.
[9]王洋,姜鹏,马丽丽,等.岩盐气溶胶疗法在尘肺病康复治疗中的临床疗效观察[J].大家健康,2014,8(11):134-135.
[10]崔桂华.岩盐气溶胶治疗硅肺的临床疗效观察[J].中国疗养医学,2017,26(10):1023-1025.
[11]熊政,张艳霞,焦深山.岩盐气溶胶疗法在支气管哮喘中临床疗效分析[J].中国医疗前沿,2013,8(17):27-28.
[12]李红艳,翁恒,王琳,等.岩盐气溶胶疗法治疗支气管哮喘患者的临床疗效及机制研究[J].中华结核和呼吸杂志,2013,36(6):460-461.
[13]方积乾,陆盈.现代统计学[M].北京:人民卫生出版社,2002:118.
[14]邱新香,陈慈珊,巫带花,等.尘肺患者心理状况及其生活质量研究进展[J].中国职业医学,2008,35(6):521-524.
[15]邱新香,郝元涛,梁智平,等.尘肺患者生活质量的相关因素研究[J].中国卫生统计,2011,28(3):233-236.
[16]田银君,刘前桂,李金红,等.多学科、综合性肺康复对老年尘肺患者的效果[J].中国康复医学,2017,23(3):352-357.
[17]苑云杰,苑树君,杨平,等.盐岩气溶胶疗法对老年肺尘埃沉着病患者疗效及生存质量的影响[J].中国老年学,2016,36(23):6015-6016.
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