耳穴刺络放血合补肾安神胶囊治疗顽固性失眠的临床观察
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摘要
目的:比较耳穴刺络放血配合补肾安神胶囊与单纯口服补肾安神胶囊治疗顽固性失眠的疗效差异。方法:将90例顽固性失眠患者随机分成3组,耳穴刺络放血配合补肾安神胶囊组(治疗组)30例,口服补肾安神胶囊组(对照1组)30例,口服艾司唑仑组(对照2组)30例。治疗组采用耳穴(耳尖、神门)刺络放血,并配合口服补肾安神胶囊;对照1组采用口服补肾安神胶囊;对照2组采用口服艾司唑仑片。观察3组患者的疗效及焦虑抑郁变化情况,并进行比较。结果:治疗组总有效率为86.7%,对照1组总有效率为80.0%,对照2组总有效率为83.3%,治疗组优于对照1组(P<0.05);治疗组患者焦虑抑郁状态改善率为90.0%,对照1组患者焦虑抑郁状态改善率为70.0%,对照2组焦虑抑郁状态改善率为26.7%。治疗组明显优于对照1组和对照2组(P<0.01)。结论:耳穴刺络放血配合补肾安神胶囊治疗顽固性失眠不仅疗效显著,且能改善其焦虑抑郁状态。
Objective: To compare the efficacy of auricular bloodletting combined with Bushen Anshen capsule and Bushen Anshen capsule in the treatment of intractable insomnia. Method: The 90 patients with intractable insomnia were randomly divid-ed into three groups: auricular bloodletting combined Bushen Anshen capsule group(treatment group), Bushen Anshen capsule group(control group 1), and estazolam group(control group 2), each 30 cases. The clinical efficacy and the changes of the anx-iety-depression of the three groups were observed after the treatment. Results: The total effective rate of the treatment group was86.7%, the control group 1 was 80.0%, and the control group was 83.3%. The effects of the treatment group was better than the control group 1(P<0.05). The improvement rate of anxiety-depression in treatment group was 90.0%, in control group was70.0%, and in control group 2 was 26.7%, the improvement rate of treatment group was significantly better than control group1 and control group2(P<0.01). Conclusion: Auricular bloodletting combined with Bushen Anshen capsule not only has good effects on intractable insomnia, but also can improve the anxiety-depression state.
Objective: To compare the efficacy of auricular bloodletting combined with Bushen Anshen capsule and Bushen Anshen capsule in the treatment of intractable insomnia. Method: The 90 patients with intractable insomnia were randomly divid-ed into three groups: auricular bloodletting combined Bushen Anshen capsule group(treatment group), Bushen Anshen capsule group(control group 1), and estazolam group(control group 2), each 30 cases. The clinical efficacy and the changes of the anx-iety-depression of the three groups were observed after the treatment. Results: The total effective rate of the treatment group was86.7%, the control group 1 was 80.0%, and the control group was 83.3%. The effects of the treatment group was better than the control group 1(P<0.05). The improvement rate of anxiety-depression in treatment group was 90.0%, in control group was70.0%, and in control group 2 was 26.7%, the improvement rate of treatment group was significantly better than control group1 and control group2(P<0.01). Conclusion: Auricular bloodletting combined with Bushen Anshen capsule not only has good effects on intractable insomnia, but also can improve the anxiety-depression state.
引文
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[11]李佩芸.耳尖放血配合耳压法治疗原发性失眠症的临床研究[D].广州:广州中医药大学,2010.
[2]夏朝云,夏承义,邓世平,等.夏氏睡眠1号治疗虚证型失眠症60例临床观察[J].中医杂志,2007,48(1):38-40.
[3]许雪梅,王伟志.针刺配合枣仁安神胶囊治疗失眠30例[J].河南中医,2014,34(4):703-704.
[4]张飚.“枣柏汤”治疗失眠38例临床观察[J].江苏中医药,2011,43(12):32-33.
[5]孟凡颖.电针治疗中、重度失眠62例临床分析[J].中国医药导报,2011,8(4):90-91.
[6]王磊,黄荣高,陈进法,等.多元时间针法治疗失眠症疗效对照观察[J].中国针灸,2012,32(4):297-298.
[7]中华人民共和国卫生部.中药新药临床研究指导原则[S].1993:186-187.
[8]中华医学会精神科分会.中国精神障碍分类与诊断标准[M].3版.济南:山东科学技术出版社,2001:105-118.
[9]肖传实,原天尚.综合医院精神卫生学[M]..北京:人民军医出版社,2003:185.
[10]张璞璘,高希言,魏玉龙,等.针刺四神聪穴治疗失眠的多中心随机对照研究[J].中医杂志,2008,49(8):712-714.
[11]李佩芸.耳尖放血配合耳压法治疗原发性失眠症的临床研究[D].广州:广州中医药大学,2010.