利奈唑胺致白细胞减少1例
摘要
<正>1病例资料患者,男,75岁,1周前无明显诱因出现右侧肢体肿胀、疼痛,活动受限,局部皮温高,在当地诊所输液(具体药物不详)治疗后,症状无明显好转。2018年2月28日转入我院,门诊血常规提示:白细胞计数(WBC) 20.8×109·L~(-1),中性粒细胞84.8%,红细胞计数(RBC)为2.49×1012·L~(-1),血红蛋白(Hb) 85 g·L~(-1),血糖14.92 mmol·L~(-1),白蛋白22. 8 g·L~(-1),肌红蛋白174.79 ng·m L~(-1)(提示肌肉受损),右侧大腿较左侧大
引文
[1]张琴,欧阳林旗,胡炜航,等.利奈唑胺谷浓度治疗药物监测的初步研究[J].中南药学,2018,20(1):138-141.
[2]朱熙,刘丽萍,胡伟,等.利奈唑胺致血液系统不良反应的回顾性研究[J].医药导报,2017,36(5):579-583.
[3]LI Y,XU W.Efficacy and safety of linezolid compared with other treatments for skin and soft tissue infections:a metaanalysis[J].Bios Rep,2018,38(1):1-9.
[4]MIKAMO H,TAKESUE Y,IWAMOTO Y,et al.Efficacy,safety and pharmacokinetics of tedizolid versus linezolid in patients with skin and soft tissue infections in Japan-results of a randomised,multicentre phase 3 study[J].J Infect Chem,2018,24(1):434-442.
[5]KHATRI S K,ATHNANAND M R,NIKHILA R,et al.Formulation and evaluation of wound healing activity of linezolid topical preparations on diabetic rats[J].Int J App Pharm,2016,8(3):30-36.
[6]吉别克·努尔孜汗,马佳萍.利奈唑胺引发血液反应不良的特点以及安全用药分析[J].中国当代医药,2017,24(18):78-80.
[7]林伟斌,彭玲玲,彭海莹,等.前列地尔注射液致过敏性休克1例[J].中南药学,2018,16(2):282-283.
[8]赵文艳,张健.利奈唑胺的血液系统毒性反应及其防治[J].药物不良反应杂志,2012,14(5):294-298.
[9]TAKAHASHI Y,TAKESUE Y,NAKAJIMA K,et al.Risk factors associated with the development of thrombocytopenia in patients who received linezolid therapy[J].J Infect Chem,2011,17(3):382-387.
[2]朱熙,刘丽萍,胡伟,等.利奈唑胺致血液系统不良反应的回顾性研究[J].医药导报,2017,36(5):579-583.
[3]LI Y,XU W.Efficacy and safety of linezolid compared with other treatments for skin and soft tissue infections:a metaanalysis[J].Bios Rep,2018,38(1):1-9.
[4]MIKAMO H,TAKESUE Y,IWAMOTO Y,et al.Efficacy,safety and pharmacokinetics of tedizolid versus linezolid in patients with skin and soft tissue infections in Japan-results of a randomised,multicentre phase 3 study[J].J Infect Chem,2018,24(1):434-442.
[5]KHATRI S K,ATHNANAND M R,NIKHILA R,et al.Formulation and evaluation of wound healing activity of linezolid topical preparations on diabetic rats[J].Int J App Pharm,2016,8(3):30-36.
[6]吉别克·努尔孜汗,马佳萍.利奈唑胺引发血液反应不良的特点以及安全用药分析[J].中国当代医药,2017,24(18):78-80.
[7]林伟斌,彭玲玲,彭海莹,等.前列地尔注射液致过敏性休克1例[J].中南药学,2018,16(2):282-283.
[8]赵文艳,张健.利奈唑胺的血液系统毒性反应及其防治[J].药物不良反应杂志,2012,14(5):294-298.
[9]TAKAHASHI Y,TAKESUE Y,NAKAJIMA K,et al.Risk factors associated with the development of thrombocytopenia in patients who received linezolid therapy[J].J Infect Chem,2011,17(3):382-387.