加味黄连膏联合肛管直肠微波仪治疗肛窦炎的疗效观察
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摘要
目的观察加味黄连膏联合肛管直肠微波仪治疗肛窦炎患者的临床效果。方法将60例肛窦炎患者随机分为加味黄连膏治疗组(n=20)、马应龙膏治疗组(n=20)及对照组(n=20)。加味黄连膏组、马应龙组及对照组分别采用加味黄连膏、马应龙膏、医用凡士林药膏纳入肛管直肠,同时予直肠微波仪行肛管直肠微波理疗20 min。各组均隔天行一次治疗,共7次,2周后结束。观察各组患者治疗前后的临床症状、体征及疗效、恢复情况等相关指标,并对比分析。结果各组患者经治疗后,加味组总有效率为90%,马应龙组总有效率为55%,对照组总有效率为20%,各组疗效比较,差异有统计学意义(P<0.01)。加味组及马应龙组治疗效果优于对照组(P<0.05);同时,加味组比马应龙组治疗效果较好(P<0.05)。各组治疗前症状体征总积分比较,差异无统计学意义(P>0.05);各组治疗后症状总积分比较,差异有统计学意义(P<0.01);与对照组比较,加味组及马应龙组症状总积分较好(P<0.05);同时,加味组对比马应龙组症状总积分较好(P<0.05)。各组复发情况比较,差异有统计学意义(P<0.01);加味组较对照组复发率低(P<0.05),加味组与马应龙组复发率比较无统计学差异(P>0.05),马应龙组与对照组复发率比较无统计学差异(P>0.05)。各组患者均未发生不良反应。结论加味黄连膏联合肛管直肠微波仪治疗肛窦炎疗效好、复发少。
Objective To examine the clinical effects of Jiawei Huanglian ointment combined with anal rectal microwave on anal sinusitis. Methods Sixty patients with anal sinusitis were recruited and randomly divided into three groups of 20 to be treated respectively with Jiawei Huanglian ointment, MaYinglong Musk Hemorrhoids Ointment and Vaseline(control group). The two ointments and Vaseline were applied into the anus and rectum, followed by 20 minutes of anal rectal microwave therapy. Each group was treated every other day for 7 times during two weeks. Clinical symptoms, signs, effects, recovery and other related indicators of each group were observed and compared. Results Response rate was 90% for Jiawei Huanglian, 55% for MaYinglong, and 20% for the controls. The inter-group differences were statistically significant(P<0.01). Outcomes of Jiawei group and Mayinglong group were better than that of the controls(P<0.05). Jiawei outperformed MaYinglong(P<0.05). Differences in assessment of symptoms and signs, which were absent before treatment(P>0.05), were observed after treatment(P<0.01). Compared with the control group, the assessment of symptoms and signs of Jiawei group and Ma Yinglong group produced better(P<0.05). Assessment of symptoms and signs of Jiawei group were better than those of Ma Yinglong group(P<0.05). There were significant differences in the relapse rate of each group(P<0.01). Recurrence rate was lower in Jiawei group than in control group(P<0.05).There was no significant difference between Jiawei group and Ma Yinglong group in relapse rate(P>0.05). There was no statistical difference in the relapse rate between Ma Yinglong group and the control group(P>0.05). No adverse reaction was observed in any of three groups of patients. Conclusion Jiawei Huanglian ointment combined with anorectal microwave can produce effective treatment for anal sinusitis with less recurrence.
Objective To examine the clinical effects of Jiawei Huanglian ointment combined with anal rectal microwave on anal sinusitis. Methods Sixty patients with anal sinusitis were recruited and randomly divided into three groups of 20 to be treated respectively with Jiawei Huanglian ointment, MaYinglong Musk Hemorrhoids Ointment and Vaseline(control group). The two ointments and Vaseline were applied into the anus and rectum, followed by 20 minutes of anal rectal microwave therapy. Each group was treated every other day for 7 times during two weeks. Clinical symptoms, signs, effects, recovery and other related indicators of each group were observed and compared. Results Response rate was 90% for Jiawei Huanglian, 55% for MaYinglong, and 20% for the controls. The inter-group differences were statistically significant(P<0.01). Outcomes of Jiawei group and Mayinglong group were better than that of the controls(P<0.05). Jiawei outperformed MaYinglong(P<0.05). Differences in assessment of symptoms and signs, which were absent before treatment(P>0.05), were observed after treatment(P<0.01). Compared with the control group, the assessment of symptoms and signs of Jiawei group and Ma Yinglong group produced better(P<0.05). Assessment of symptoms and signs of Jiawei group were better than those of Ma Yinglong group(P<0.05). There were significant differences in the relapse rate of each group(P<0.01). Recurrence rate was lower in Jiawei group than in control group(P<0.05).There was no significant difference between Jiawei group and Ma Yinglong group in relapse rate(P>0.05). There was no statistical difference in the relapse rate between Ma Yinglong group and the control group(P>0.05). No adverse reaction was observed in any of three groups of patients. Conclusion Jiawei Huanglian ointment combined with anorectal microwave can produce effective treatment for anal sinusitis with less recurrence.
引文
[1]张承国.中药保留灌肠与穴位埋线、龈交穴挑刺联合治疗慢性肛窦炎的疗效观察[J].中国现代药物应用,2018,12(12):117-119.
[2]罗绪.蒲柏止痛汤保留灌肠对肛窦炎患者疗效及安全性观察[J].深圳中西医结合杂志,2018,28(9):48-50.
[3]陈波,张晟,王秋平,等.参柏汤保留灌肠联合生物刺激反馈仪治疗湿热下注型肛窦炎的临床研究[J].世界中西医结合杂志,2018,13(4):514-516,520.
[4]程东红,杜宇鹏,王超.苦参清湿液保留灌肠治疗肛窦炎的临床观察[J].临床医药文献电子杂志,2018,5(14):136-137.
[5]安阿玥.肛肠病学[M].北京:人民卫生出版社,2005:250.
[6]国家中医药管理局.中医肛肠科疾病诊断疗效标准[S].南京:南京大学出版社,1995:341.
[7]冯子轩,黄凌云,孙玉才.栀子金花汤保留灌肠治疗实证肛窦炎60例[J].中国中西医结合外科杂志,2015,21(6):619-620.
[8]黄乃健.中国肛肠病学[M].济南:山东科学技术出版社,1996:790-793.
[9]Gun KH,Chan HK,Sup KH,et al.Sodium picosulfate with magnesium citrate(SPMC)Plus laxative is a good alternative to conventional large volume polyethylene glycol in bowel Preparation:A multicenter randomized single-blinded trial[J].Gut&Liver,2015,9(4):494-501.
[10]李金元.加味苦参汤联合保留灌肠治疗肛窦炎的临床观察[J].江西中医药,2018,49(3):49-51.
[11]祁卫华,李娟.止痛如神汤加肛泰痔疮栓治疗肛窦炎的临床疗效[J].临床医药文献电子杂志,2018,5(16):131.
[12]蔡碧波,吴鹏.肛窦炎178例治疗分析[J].昆明医科大学学报,2014,35(3):145-147.
[13]吴定奇,胡建文,梁小霞,等.中药熏洗坐浴和加味四黄膏外敷治疗肛窦炎临床观察[J].四川中医,2015,33(4):149-150.
[14]崔凤东.肛隐窝炎的发病机理与隐窝的愈合及肛管的血液供应[J].国外医学·外科学分册.1989,16(4):196-197.
[15]Frank W.Coloproctology[J].J Pediatr Surg,1985,7(1):7.
[16]李雨农.中华肛肠病学[M].重庆:科学技术出版社重庆分社,1990:428.
[17]高月晋.痔ろうへの新しぃァブノチ[J].大肠肛门志.1985,38(3):401-406.
[18]韩宝,张燕生.中国肛肠病诊疗学[M].北京:人民军医出版社,2011:201.
[19]王沛,李曰庆,张燕生.中医外科治疗大成[M].石家庄:河北科学技术出社,1997:415.
[20]张涛.加味乙字汤治疗湿热下注型慢性肛窦炎的临床疗效及对疼痛、复发率的影响[J].临床医学研究与实践,2018,3(9):121-122.
[21]王小林,耿学斯.肛窦炎的中医药疗效进展[J].云南中医中药杂志,2014,35(1):64-65.
[22]耿少民,王立馨,邓云权.止痛如神汤加洗必泰痔疮栓治疗肛窦炎疗效观察[J].现代中医药,2017,37(6):59-60.
[23]叶敏馥.奥硝唑栓治疗肛窦炎的临床观察[J].临床合理用药,2009,2(7):51.
[24]黄鸿飞.中药保留灌肠配合微波治疗肛窦炎39例观察[J].实用中医药杂志,2016,32,(4):323.
[25]陈子胜,高宝良,周秀扣.微波治疗肛窦炎223例[J].中华物理医学与康复杂志,2003,11(7):44.
[2]罗绪.蒲柏止痛汤保留灌肠对肛窦炎患者疗效及安全性观察[J].深圳中西医结合杂志,2018,28(9):48-50.
[3]陈波,张晟,王秋平,等.参柏汤保留灌肠联合生物刺激反馈仪治疗湿热下注型肛窦炎的临床研究[J].世界中西医结合杂志,2018,13(4):514-516,520.
[4]程东红,杜宇鹏,王超.苦参清湿液保留灌肠治疗肛窦炎的临床观察[J].临床医药文献电子杂志,2018,5(14):136-137.
[5]安阿玥.肛肠病学[M].北京:人民卫生出版社,2005:250.
[6]国家中医药管理局.中医肛肠科疾病诊断疗效标准[S].南京:南京大学出版社,1995:341.
[7]冯子轩,黄凌云,孙玉才.栀子金花汤保留灌肠治疗实证肛窦炎60例[J].中国中西医结合外科杂志,2015,21(6):619-620.
[8]黄乃健.中国肛肠病学[M].济南:山东科学技术出版社,1996:790-793.
[9]Gun KH,Chan HK,Sup KH,et al.Sodium picosulfate with magnesium citrate(SPMC)Plus laxative is a good alternative to conventional large volume polyethylene glycol in bowel Preparation:A multicenter randomized single-blinded trial[J].Gut&Liver,2015,9(4):494-501.
[10]李金元.加味苦参汤联合保留灌肠治疗肛窦炎的临床观察[J].江西中医药,2018,49(3):49-51.
[11]祁卫华,李娟.止痛如神汤加肛泰痔疮栓治疗肛窦炎的临床疗效[J].临床医药文献电子杂志,2018,5(16):131.
[12]蔡碧波,吴鹏.肛窦炎178例治疗分析[J].昆明医科大学学报,2014,35(3):145-147.
[13]吴定奇,胡建文,梁小霞,等.中药熏洗坐浴和加味四黄膏外敷治疗肛窦炎临床观察[J].四川中医,2015,33(4):149-150.
[14]崔凤东.肛隐窝炎的发病机理与隐窝的愈合及肛管的血液供应[J].国外医学·外科学分册.1989,16(4):196-197.
[15]Frank W.Coloproctology[J].J Pediatr Surg,1985,7(1):7.
[16]李雨农.中华肛肠病学[M].重庆:科学技术出版社重庆分社,1990:428.
[17]高月晋.痔ろうへの新しぃァブノチ[J].大肠肛门志.1985,38(3):401-406.
[18]韩宝,张燕生.中国肛肠病诊疗学[M].北京:人民军医出版社,2011:201.
[19]王沛,李曰庆,张燕生.中医外科治疗大成[M].石家庄:河北科学技术出社,1997:415.
[20]张涛.加味乙字汤治疗湿热下注型慢性肛窦炎的临床疗效及对疼痛、复发率的影响[J].临床医学研究与实践,2018,3(9):121-122.
[21]王小林,耿学斯.肛窦炎的中医药疗效进展[J].云南中医中药杂志,2014,35(1):64-65.
[22]耿少民,王立馨,邓云权.止痛如神汤加洗必泰痔疮栓治疗肛窦炎疗效观察[J].现代中医药,2017,37(6):59-60.
[23]叶敏馥.奥硝唑栓治疗肛窦炎的临床观察[J].临床合理用药,2009,2(7):51.
[24]黄鸿飞.中药保留灌肠配合微波治疗肛窦炎39例观察[J].实用中医药杂志,2016,32,(4):323.
[25]陈子胜,高宝良,周秀扣.微波治疗肛窦炎223例[J].中华物理医学与康复杂志,2003,11(7):44.