活血化瘀法治疗骶髂关节受累型白塞病54例临床疗效观察
摘要
目的观察活血化瘀法治疗骶髂关节受累型白塞病(Behcet's disease,BD)的临床疗效观察。方法挑选于我院就诊的符合标准的骶髂关节受累型白塞病患者54例,将患者平均分为治疗组和对照组各27例。两组均给予白塞病基础治疗,对照组予以口服沙利度胺片+柳氮磺吡啶,治疗组予以沙利度胺片+我院自制中成药骨蚀胶囊,同时两组均予以骶髂部推拿按摩治疗。两组均以2个月为治疗疗程。观察对比治疗前后两组疼痛分级指数(PRI)、相关指标的变化(晨僵时间、指地距、枕墙距、Schober征)、治疗后的复发情况(是否有症状的再次加重)。结果 (1)治疗组比对照组疗效显著(P<0.05)。(2)治疗组患者疼痛分级指数(PRI)降低明显优于对照组,比较差异具有统计学意义(P<0.05)。(3)治疗组的相关指标的改善情况优于对照组(P<0.05)。(4)治疗组患者复发率(3个月内)明显低于对照组(P<0.05)。结论活血化瘀法治疗骶髂关节受累型白塞病有显著疗效。
引文
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[2] 秦涛,程永华,郭超,李亚.白塞湿清方治疗湿热壅盛型白塞病临床观察.风湿病与关节炎.2017,6(5):31
[3] Ishido T ,Horita N ,Takeuchi M ,et al.Clinical manifestations of Behcet's disease depending on sex and age:results from Japanese nationwide registration[J].Rheumatology (Oxford) 2017,56 (11):1918.
[4] Yurdakul S,Yazici H,Tuzun Y,et al.The arthritis of Behqet's disease:a prospective study[J].Ann Rheum Dis,1983,42:505.
[5] 孙利平,邓雪蓉,张卓莉,等.白塞病关节受累的临床特点.现代医学与健康研究,2018,2(5):149.
[6] Dilsen N,Konice M,Aral O.Why Behcet's disease should be accepted as a seronegative arthritis.In:Lehner T,Barnes CG,editors,Recent Advances in Behcet's Disease[J].London:Royal Society of Medicine Services,1986:281.
[7] Chang HK,Lee DH,Jung SM,et al.The comparison between Behcet's disease and spondyloarthritides:does Behcet's disease belong to the spondyloarthropathy complex[J].J Korean Med Sci,2002,17(4):524.
[8] Olivieri I,Gemignani G,Camerini E,et al.Computed tomography of the sacroiliac joints in four patients with Behcet's syndrome:confirmation of sacroiliitis [J].Br J Rheumatol,1990,29(4):264.
[9] 曹元华 .日本新修订的白塞综合征诊断与分期及临床严重度标准[J].国际皮肤性病学杂志 ,2006,32(1):56.
[10] 麦凤香,李国徽,王军.温针灸治疗骶髂关节炎的临床研究[J].中国当代医药,2016,31(15):2226.
[11] 呼家佳,张成梁,王英,等.产后骶髂关节炎-病例报告及文献综述[J].中国疼痛医学杂志 ,2015,21(8):633,637.
[12] 魏晓松.骨蚀胶囊对激素性股骨头缺血性坏死骨组织形态学的影响[J].辽宁中医学院硕士学位论文.2013.
[13] 宗田大.膝痛诊断与治疗[M].郑州:河南科学技术出版社,2011:12.