橘红挥发油的提取及包合工艺研究

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英文篇名：Extraction and inclusion technology of volatile oil from exocarpium citrri rubrum 作者：张海鸣 ; 范斌 ; 费超 ; 闫明 ; 彭娟 ; 聂颖兰 ; 闫寒 英文作者：ZHANG Hai-ming;FAN Bin;FEI Chao;YAN Ming;PENG Juan;NIE Yin-lan;YAN Han;Experimental Research Center, China Academy of Chinese Medical Sciences;State Key Laboratory Breeding Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences;Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Beijing Normal University; 关键词：橘红 ; 挥发油 ; β-环糊精 ; 包合工艺 ; 提取工艺 ; 正交试验 英文关键词：Exocarpium crtri rubrum;;Volatile oil;;β-cyclodextrin;;Inclusion technology;;Extraction technology;;Orthogonal test 中文刊名：BXYY 英文刊名：China Journal of Traditional Chinese Medicine and Pharmacy 机构：中国中医科学院医学实验中心;中国中医科学院道地药材国家重点实验室培育基地;北京师范大学中药资源保护与利用北京市重点实验室; 出版日期：2018-09-01 出版单位：中华中医药杂志 年：2018 期：v.33 基金：中央级公益性科研院所基本科研业务费专项资金(No.zz2017007);; 中央本级重大增减支项目(No.2060302)~~ 语种：中文; 页：BXYY201809114 页数：3 CN：09 ISSN：11-5334/R 分类号：421-423

摘要

目的:优选橘红挥发油的提取及β-环糊精包合的最佳工艺。方法:以挥发油的提取量为考察指标,采用正交试验优选挥发油提取工艺;以挥发油包合率为考察指标,优选β-环糊精包合工艺。结果:挥发油最佳提取工艺为:加10倍量的水,浸泡30min,提取8h;挥发油包合的最佳工艺为:采用饱和水溶液法,挥发油与β-环糊精的用量比为1∶10,包合温度50℃,包合时间2h。结论:优选的橘红挥发油提取工艺提油率较高,包合工艺稳定可行。
        Objective: To optimize the process of volatile oil extraction and β-cyclodextrin(β-CD) inclusion from exocarpium citri rubrum. Methods: Taking the extraction of volatile oil as an investigation index, the extraction process of volatile oil is selected by orthogonal test, and the inclusion rate of volatile oil is used as an index to optimize the inclusion process of β-cyclodextrin. Results: The best optimized extraction conditions were: adding 10 times the amount of water, soaking 30 min, extracting 8 h. The best optimal inclusion conditions were: using saturated aqueous solution method, the ratio of volatile oil to β-cyclodextrin was 1∶10, the inclusion temperature was 50℃, and the inclusion time was 2 h. Conclusion: The optimized extraction technology has a high rate of oil yield. The optimized inclusion technology is stable and feasible.

引文

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