超高效液相色谱-串联质谱法在水产品硝基呋喃类代谢物检测应用的研究进展
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摘要
建立高效的水产品硝基呋喃类代谢物检测分析方法,是保障我国水产品质量安全的一种有效风险监测技术手段。超高效液相色谱-串联质谱法(UPLC-MS/MS)具有分析时间短、检出限低、灵敏度高等优点,可满足水产品硝基呋喃类代谢物的定性和定量分析。介绍了硝基呋喃类药物种类、特点及其危害,对UPLC-MS/MS技术在水产品硝基呋喃类代谢物的检测应用做了简要综述。
Establishing an efficient method for the detection of nitrofurans metabolites in aquatic products is an effective risk monitoring technology to ensure the quality and safety of aquatic products in China. Ultra-high performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS) has the advantages of short analysis time, low detection limit and high sensitivity. It can satisfy the qualitative and quantitative analysis of nitrofuran metabolites in aquatic products. In this paper,the types,physicochemical properties and hazards of nitrofurans were introduced. The application of UPLC-MS/MS in the detection of nitrofurans metabolites in aquatic products was briefly reviewed.
Establishing an efficient method for the detection of nitrofurans metabolites in aquatic products is an effective risk monitoring technology to ensure the quality and safety of aquatic products in China. Ultra-high performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS) has the advantages of short analysis time, low detection limit and high sensitivity. It can satisfy the qualitative and quantitative analysis of nitrofuran metabolites in aquatic products. In this paper,the types,physicochemical properties and hazards of nitrofurans were introduced. The application of UPLC-MS/MS in the detection of nitrofurans metabolites in aquatic products was briefly reviewed.
引文
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[10]高月明,冯笑军,李倩莹.超高效液相色谱-串联质谱法测定淡水鱼中硝基呋喃类代谢物残留[J].食品安全质量检测学报,2017(8):3 231-3 236.
[11]王狄,张嘉楠.超高效液相色谱串联质谱法对水产品中硝基呋喃代谢物的测定[J].河北渔业,2016(7):47-51.
[12]刘柏林,谢继安,赵紫微,等.超高效液相色谱-串联质谱法测定动物源性食品中硝基呋喃代谢物[J].食品安全质量检测学报,2014,5(2):421-427.
[13]孙涛,胡开峰,乔昆云,等.超高效液相色谱-串联质谱法测定水产品中硝基呋喃代谢物残留[J].分析仪器,2010(5):27-31.
[14]杨奕,邵兵.超高压液相色谱-串联质谱法测定虾中硝基呋喃代谢物[J].食品安全质量检测学报,2013(1):135-140.
[2]徐伟,耿士伟,刘路,等.硝基呋喃类药物及其代谢物检测方法的研究进展[J].天津农业科学,2018, 24(8):16-20.
[3]徐一平,胥传来.动物源食品中硝基呋喃类物质及其代谢物残留的检测技术研究[J].食品科学,2007(10):590-593.
[4]胡红芹,张坤.饲料中药物残留及其检测方法研究进展[J].农产品加工,2017(4):65-67,70.
[5]王媛,蔡友琼,贾东芬,等.高效液相色谱法检测水产品中硝基呋喃类代谢物残留量[J].分析试验室,2009,28(12):86-91.
[6]马帅,王蒙,韩平,等.QuEChERS-超高效液相色谱-串联质谱法在食品真菌毒素检测中应用的研究进展[J].食品安全质量检测学报,2016(8):3 020-3 024.
[7]曾亚军,王淑萍,林厚文.超高效液相-四级杆-飞行时间质谱在复杂成分快速筛选和鉴定方面的应用[J].亚太传统医药,2017,13(5):54-58.
[8]王跃,尹燕杰,赵丹,等.超高效液相色谱-串联质谱法测定水产品中的硝基呋喃代谢物[J].化学分析计量,2018, 27(5):43-47.
[9]杨惠宇,张惠峰.超高效液相色谱-同位素稀释串联质谱法测定水产品中硝基呋喃类代谢物残留[J].河北渔业,2017(11):50-53.
[10]高月明,冯笑军,李倩莹.超高效液相色谱-串联质谱法测定淡水鱼中硝基呋喃类代谢物残留[J].食品安全质量检测学报,2017(8):3 231-3 236.
[11]王狄,张嘉楠.超高效液相色谱串联质谱法对水产品中硝基呋喃代谢物的测定[J].河北渔业,2016(7):47-51.
[12]刘柏林,谢继安,赵紫微,等.超高效液相色谱-串联质谱法测定动物源性食品中硝基呋喃代谢物[J].食品安全质量检测学报,2014,5(2):421-427.
[13]孙涛,胡开峰,乔昆云,等.超高效液相色谱-串联质谱法测定水产品中硝基呋喃代谢物残留[J].分析仪器,2010(5):27-31.
[14]杨奕,邵兵.超高压液相色谱-串联质谱法测定虾中硝基呋喃代谢物[J].食品安全质量检测学报,2013(1):135-140.