急性一氧化碳中毒规范化救治分析
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摘要
目的探讨急性一氧化碳中毒(acute carbon monoxide poisoning,ACOP)的处置方法。方法将ACOP患者183例按就诊时间分为对照组85例,观察组98例。观察组按规范化统一标准救治,对照组按常规治疗。比较2组的临床疗效、意识恢复时间、迟发性脑病发生率。结果 2组临床疗效比较差异无统计学意义(P>0.05),观察组中度和重度中毒患者的平均意识恢复时间短于对照组(P<0.05),观察组迟发性脑病发生率低于对照组(P<0.05)。结论 ACOP规范化救治有利于快速救治ACOP,并减少迟发性脑病发生率。
Objective To improve handling of acute carbon monoxide poisoning(ACOP).Methods A total of 183 cases of ACOP patients were divided into control group 85 cases and observation group 98 cases by treatment time. The observation group was treated by standardized treatment,while the control group was by conventional treatment.The clinical efficacy,consciousness recovery time and the incidence of delayed encephalopathy of two groups were compared.Results Clinical efficacy of two groups was not statistically significant(P>0.05),while average consciousness recovery time of moderate and severe patients in observation group was shorter than that of control group(P< 0.05),and the incidence of delayed encephalopathy of observation group was lower than that of control group(P<0.05).Conclusion Application of standardized treatment of ACOP contributes to rapid treatment and reduces the incidence of delayed encephalopathy of ACOP.
Objective To improve handling of acute carbon monoxide poisoning(ACOP).Methods A total of 183 cases of ACOP patients were divided into control group 85 cases and observation group 98 cases by treatment time. The observation group was treated by standardized treatment,while the control group was by conventional treatment.The clinical efficacy,consciousness recovery time and the incidence of delayed encephalopathy of two groups were compared.Results Clinical efficacy of two groups was not statistically significant(P>0.05),while average consciousness recovery time of moderate and severe patients in observation group was shorter than that of control group(P< 0.05),and the incidence of delayed encephalopathy of observation group was lower than that of control group(P<0.05).Conclusion Application of standardized treatment of ACOP contributes to rapid treatment and reduces the incidence of delayed encephalopathy of ACOP.
引文
[1]高春锦,葛环,赵立明,等.一氧化碳中毒临床治疗指南(一)[J].中华航海医学与高气压医学杂志,2012,19(2):127-128,封3.
[2]葛环,高春锦,赵立明,等.一氧化碳中毒临床治疗指南(二)[J].中华航海医学与高气压医学杂志,2012,19(5):315-317.
[3]康建飞,周珏榕,张陆弟.高压氧救治重症一氧化碳中毒286例无迟发型脑病发生临床分析[J].临床内科杂志,2013,30(6):423.
[4]魏中兴.急性一氧化碳中毒急救的临床观察.[J].中国医药指南,2013,11(33):129-130.
[5]刘北.不同时间窗高压氧治疗一氧化碳中毒临床疗效观察[J].山东医药,2013,53(37):84-85.
[6]李文.高压氧治疗一氧化碳中毒[J].中国医学创新,2013,10(5):158-159.
[7]葛环,高春锦,赵立明,等.一氧化碳中毒临床治疗指南(四)[J].中华航海医学与高气压医学杂志,2013,20(5):356-358.
[8]郭军,孟郊,韩彤.一氧化碳中毒与中毒后迟发性脑病的大脑磁共振成像比较[J].中华劳动卫生职业病杂志,2014,32(7):533-536.
[9]马琳琳,葛环,武连华,等.早期高压氧联合激素干预预防一氧化碳中毒大鼠迟发性脑病的实验研究[J].中华航海医学与高气压医学杂志,2013,20(1):16-18.
[10]王艳芳,杨立波,米玉霞,等.通心络胶囊治疗急性一氧化碳中毒迟发性脑病的临床疗效观察[J].河北医科大学学报,2013,34(8):921-923.
[11]马兴义.大剂量地塞米松联合高压氧救治急性一氧化碳中毒的临床研究[J].中国医学创新,2013,10(23):45-47.
[12]石富铭.糖皮质激素预防成人急性一氧化碳中毒后迟发性脑病的临床观察[J].中国临床医生,2013,41(11):43-44.
[13]李胜迪,陈丹,任琳.奥拉西坦治疗急性一氧化碳中毒迟发性脑病的疗效分析[J].中国医学工程,2014,22(4):92-93.
[14]张华瑞,张悦凤.奥拉西坦联合长春西汀注射液治疗一氧化碳中毒迟发性脑病的临床观察[J].重庆医学,2014,43(8):930-931,934.
[2]葛环,高春锦,赵立明,等.一氧化碳中毒临床治疗指南(二)[J].中华航海医学与高气压医学杂志,2012,19(5):315-317.
[3]康建飞,周珏榕,张陆弟.高压氧救治重症一氧化碳中毒286例无迟发型脑病发生临床分析[J].临床内科杂志,2013,30(6):423.
[4]魏中兴.急性一氧化碳中毒急救的临床观察.[J].中国医药指南,2013,11(33):129-130.
[5]刘北.不同时间窗高压氧治疗一氧化碳中毒临床疗效观察[J].山东医药,2013,53(37):84-85.
[6]李文.高压氧治疗一氧化碳中毒[J].中国医学创新,2013,10(5):158-159.
[7]葛环,高春锦,赵立明,等.一氧化碳中毒临床治疗指南(四)[J].中华航海医学与高气压医学杂志,2013,20(5):356-358.
[8]郭军,孟郊,韩彤.一氧化碳中毒与中毒后迟发性脑病的大脑磁共振成像比较[J].中华劳动卫生职业病杂志,2014,32(7):533-536.
[9]马琳琳,葛环,武连华,等.早期高压氧联合激素干预预防一氧化碳中毒大鼠迟发性脑病的实验研究[J].中华航海医学与高气压医学杂志,2013,20(1):16-18.
[10]王艳芳,杨立波,米玉霞,等.通心络胶囊治疗急性一氧化碳中毒迟发性脑病的临床疗效观察[J].河北医科大学学报,2013,34(8):921-923.
[11]马兴义.大剂量地塞米松联合高压氧救治急性一氧化碳中毒的临床研究[J].中国医学创新,2013,10(23):45-47.
[12]石富铭.糖皮质激素预防成人急性一氧化碳中毒后迟发性脑病的临床观察[J].中国临床医生,2013,41(11):43-44.
[13]李胜迪,陈丹,任琳.奥拉西坦治疗急性一氧化碳中毒迟发性脑病的疗效分析[J].中国医学工程,2014,22(4):92-93.
[14]张华瑞,张悦凤.奥拉西坦联合长春西汀注射液治疗一氧化碳中毒迟发性脑病的临床观察[J].重庆医学,2014,43(8):930-931,934.