氟化泡沫用于儿童龋齿防治的调查研究
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摘要
目的分析氟化泡沫在石家庄地区用于防治学龄前儿童龋齿的疗效。方法 1 276例受试者按照纳入标准随机分成试验组和对照组,每组638例。统计患龋率、龋失补牙数、龋失补牙面数以及Cariostat试验等指标分析受试者患有龋齿的情况和受试者口腔内的细菌产生酸性物质情况。试验组应用氟化泡沫对学前儿童进行干预后,分析龋活跃性及防龋效果。结果石家庄地区1 276位受试儿童的Cariostat值集中在1~1.5,患龋率随着Cariostat值的增长而升高,龋失补牙数也与Cariostat值呈正相关关系(P<0.01);干预处理后2组Cariostat值都有一定程度的下降趋势,试验组治疗前后组内Cariostat值比较,治疗后Cariostat值下降明显,相比较治疗前下降显著,差异均有统计学意义(P<0.05)。结论龋齿在石家庄地区的学龄前儿童中患病率很高,龋蚀程度相对较重,发病危险率大的儿童比重很大;使用氟化泡沫对龋齿的防治起到重要作用,值得临床推广应用。
Objective To investigate the preventive and therapeutic effects of fluorinated foam on dental caries in preschool children in Shijiazhuang area. Methods A total of 1276 subjects were randomly divided into experimental group( n = 638) and control group( n = 638) according to the internalized criteria. The incidence rate of dental caries,decay missing filling teeth,decayed missing filling surfaces and Cariostat test were observed to analyze and compare the presence of dental caries and the amount of acidic substance produced by bacteria in oral cavity of subjects. Moreover after the preschool children in exprerimental group were intervened with fluorinated foam,the activity of caries and effects of caries prevention were observed and compared between two groups. Results The Cariostat value of 1276 subjects in Shijiazhuang area was mainly between 1 ~ 1. 5. The caries prevalence rate was increased with the increase of Cariostat value. There was a positive correlation between decay missing filling teeth number and Cariostat values( P < 0. 01). After intervention,the Cariostat value had decrease trend in both groups at some certain extent. Moreover the Cariostat value was significantly decreased in experimental group,as compared with that before intervention( P < 0. 05). Conclusion The incidence rate of dental caries in preschool children in Shijiazhuang area is quite high,and the decadere degree is relatively severe,moreover the proportion of children with high risk is very high. The fluorinated foam plays an important role in prevention and treatment of dental caries and is worthy of clinical application.
Objective To investigate the preventive and therapeutic effects of fluorinated foam on dental caries in preschool children in Shijiazhuang area. Methods A total of 1276 subjects were randomly divided into experimental group( n = 638) and control group( n = 638) according to the internalized criteria. The incidence rate of dental caries,decay missing filling teeth,decayed missing filling surfaces and Cariostat test were observed to analyze and compare the presence of dental caries and the amount of acidic substance produced by bacteria in oral cavity of subjects. Moreover after the preschool children in exprerimental group were intervened with fluorinated foam,the activity of caries and effects of caries prevention were observed and compared between two groups. Results The Cariostat value of 1276 subjects in Shijiazhuang area was mainly between 1 ~ 1. 5. The caries prevalence rate was increased with the increase of Cariostat value. There was a positive correlation between decay missing filling teeth number and Cariostat values( P < 0. 01). After intervention,the Cariostat value had decrease trend in both groups at some certain extent. Moreover the Cariostat value was significantly decreased in experimental group,as compared with that before intervention( P < 0. 05). Conclusion The incidence rate of dental caries in preschool children in Shijiazhuang area is quite high,and the decadere degree is relatively severe,moreover the proportion of children with high risk is very high. The fluorinated foam plays an important role in prevention and treatment of dental caries and is worthy of clinical application.
引文
1 Kidd EAM,Fejerskov O.Essentials of dental caries.Oxford University Press,2016.
2 Simón-Soro A,Mira A.Solving the etiology of dental caries.Trends in Microbiology,2015,23:76-82.
3 熊莉华,郭重山,刘伟,等.广州市适龄儿童第一恒磨牙窝沟封闭防龋效果分析.中国公共卫生,2017,33:626-630.
4 Nehme M,Jeffery P,Mason S,et al.Erosion remineralization efficacy of gel-to-foam fluoride toothpastes in situ:a randomized clinical trial.Caries Research,2016,50:62-70.
5 Twetman S,Keller MK.Fluoride Rinses,Gels and Foams:An update of controlled clinical trials.Caries Research,2016,50:38-44.
6 Lin D,Huang B.Staining potential of acidulated phosphate fluoride(APF)foam on dental restorations in vitro.Journal of Conservative Dentistry:JCD,2015,18:30.
7 Priyono B,Kusnanto H,Santoso AS,et al.Correlation of predictions to get a new dental caries with residence area and parental socio-economic conditions in adolescents in Sleman DIY.Dental Journal(Majalah Kedokteran Gigi),2016,49:115-119.
8 苏亭娟,孙玉叶,章景丽,等.扬州市城区学龄前儿童发育性协调障碍的流行病学调查.中华疾病控制杂志,2017,21:183-186.
9 俞有健.氟化泡沫应用于幼儿早期龋齿效果观察及风险分析.中国药物警戒,2016,13:619-622.
10 郑文,倪育,茅婕.盐城市区1742名学龄前儿童发育性协调障碍流行病学调查.中国妇幼保健,2015,30:2607-2610.
11 Schaefer CE,Andaya C,Urtiaga A,et al.Electrochemical treatment of perfluorooctanoic acid(PFOA)and perfluorooctane sulfonic acid(PFOS)in groundwater impacted by aqueous film forming foams(AFFFs).Journal of hazardous materials,2015,295:170-175.
12 Liao F,Swiatowska J,Maurice V,et al.The influence of the electrolyte on chemical and morphological modifications of an iron sulfide thin film negative electrode.Physical Chemistry Chemical Physics,2015,17:619-629.
13 Wang JK,Xiong GM,Zhu M,et al.Polymer-Enriched 3D Graphene Foams for Biomedical Applications.ACS applied materials Interfaces,2015,7:8275-8283.
14 Raj S,Goel S,Sharma VL,et al.Screening for caries activity among preschool children of anganwadi centers in a north indian city.SRM Journal of Research in Dental Sciences,2015,6:1.
15 刘红,刁晓洁,万哲,等.新疆北疆地区哈萨克族12-14岁青少年龋齿患病率的流行病学调查.临床口腔医学杂志,2016,32:591-593,594.
16 Shimada A,Noda M,Matoba Y,et al.Oral lactic acid bacteria related to the occurrence and/or progression of dental caries in Japanese preschool children.Bioscience of Microbiota,Food and Health,2015,34:29-36.
17 Mc Laren L,Mc Neil DA,Potestio M,et al.Equity in children’s dental caries before and after cessation of community water fluoridation:differential impact by dental insurance status and geographic material deprivation.International Journal for Equity in Health,2016,15:24.
18 Neidell M,Shearer B,Lamster IB.Cost-Effectiveness analysis of dental sealants versus fluoride varnish in a school-based setting.Caries Research,2016,50:78-82.
19 徐小娟,刘英志,陈碧莲,等.氟化物联合五倍子水提取物对变形链球菌影响的体外研究.中国医学创新,2015,12:110-112.
20 Frantz WF,Patel JD,Maben DD,et al.Light weight thermoplastic flex foam and hybrid duct system:U.S.Patent 9,669,593.2017-6-6.
21 高海泉.氟化泡沫对儿童龋齿的预防效果分析.现代中西医结合杂志,2015,24:3029-3030,3031.
22 孙丽霞.氟化泡沫护龋在海口市幼儿园儿童龋病中的应用.湖南师范大学学报(医学版),2016,13:108-110,111.
23 梅银娥,周春泉,王向荣,等.应用氟化泡沫预防幼儿龋齿的防龋效果观察.临床口腔医学杂志,2014,30:50-51.
2 Simón-Soro A,Mira A.Solving the etiology of dental caries.Trends in Microbiology,2015,23:76-82.
3 熊莉华,郭重山,刘伟,等.广州市适龄儿童第一恒磨牙窝沟封闭防龋效果分析.中国公共卫生,2017,33:626-630.
4 Nehme M,Jeffery P,Mason S,et al.Erosion remineralization efficacy of gel-to-foam fluoride toothpastes in situ:a randomized clinical trial.Caries Research,2016,50:62-70.
5 Twetman S,Keller MK.Fluoride Rinses,Gels and Foams:An update of controlled clinical trials.Caries Research,2016,50:38-44.
6 Lin D,Huang B.Staining potential of acidulated phosphate fluoride(APF)foam on dental restorations in vitro.Journal of Conservative Dentistry:JCD,2015,18:30.
7 Priyono B,Kusnanto H,Santoso AS,et al.Correlation of predictions to get a new dental caries with residence area and parental socio-economic conditions in adolescents in Sleman DIY.Dental Journal(Majalah Kedokteran Gigi),2016,49:115-119.
8 苏亭娟,孙玉叶,章景丽,等.扬州市城区学龄前儿童发育性协调障碍的流行病学调查.中华疾病控制杂志,2017,21:183-186.
9 俞有健.氟化泡沫应用于幼儿早期龋齿效果观察及风险分析.中国药物警戒,2016,13:619-622.
10 郑文,倪育,茅婕.盐城市区1742名学龄前儿童发育性协调障碍流行病学调查.中国妇幼保健,2015,30:2607-2610.
11 Schaefer CE,Andaya C,Urtiaga A,et al.Electrochemical treatment of perfluorooctanoic acid(PFOA)and perfluorooctane sulfonic acid(PFOS)in groundwater impacted by aqueous film forming foams(AFFFs).Journal of hazardous materials,2015,295:170-175.
12 Liao F,Swiatowska J,Maurice V,et al.The influence of the electrolyte on chemical and morphological modifications of an iron sulfide thin film negative electrode.Physical Chemistry Chemical Physics,2015,17:619-629.
13 Wang JK,Xiong GM,Zhu M,et al.Polymer-Enriched 3D Graphene Foams for Biomedical Applications.ACS applied materials Interfaces,2015,7:8275-8283.
14 Raj S,Goel S,Sharma VL,et al.Screening for caries activity among preschool children of anganwadi centers in a north indian city.SRM Journal of Research in Dental Sciences,2015,6:1.
15 刘红,刁晓洁,万哲,等.新疆北疆地区哈萨克族12-14岁青少年龋齿患病率的流行病学调查.临床口腔医学杂志,2016,32:591-593,594.
16 Shimada A,Noda M,Matoba Y,et al.Oral lactic acid bacteria related to the occurrence and/or progression of dental caries in Japanese preschool children.Bioscience of Microbiota,Food and Health,2015,34:29-36.
17 Mc Laren L,Mc Neil DA,Potestio M,et al.Equity in children’s dental caries before and after cessation of community water fluoridation:differential impact by dental insurance status and geographic material deprivation.International Journal for Equity in Health,2016,15:24.
18 Neidell M,Shearer B,Lamster IB.Cost-Effectiveness analysis of dental sealants versus fluoride varnish in a school-based setting.Caries Research,2016,50:78-82.
19 徐小娟,刘英志,陈碧莲,等.氟化物联合五倍子水提取物对变形链球菌影响的体外研究.中国医学创新,2015,12:110-112.
20 Frantz WF,Patel JD,Maben DD,et al.Light weight thermoplastic flex foam and hybrid duct system:U.S.Patent 9,669,593.2017-6-6.
21 高海泉.氟化泡沫对儿童龋齿的预防效果分析.现代中西医结合杂志,2015,24:3029-3030,3031.
22 孙丽霞.氟化泡沫护龋在海口市幼儿园儿童龋病中的应用.湖南师范大学学报(医学版),2016,13:108-110,111.
23 梅银娥,周春泉,王向荣,等.应用氟化泡沫预防幼儿龋齿的防龋效果观察.临床口腔医学杂志,2014,30:50-51.
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