从痰瘀论治非酒精性脂肪肝研究进展
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摘要
非酒精性脂肪肝(non-alcoholic fatty liver disease,NAFLD)是临床常见的一类脂肪性肝病,中医学将其归属于"积聚""痰痞""肥气""胁痛"等范畴,中医学者大多认为该病的病因以痰浊、瘀血为首,病机以肝失疏泄、脾失健运、痰瘀互结为主,临证诊治或以理气祛痰为主,或以活血化瘀为主,或两者同时兼顾,相辅相成,疗效颇为显著。该文以中医的痰瘀理论为主要切入点来探讨近年来非酒精性脂肪肝的研究进展,以期能为非酒精性脂肪肝的诊断与治疗提供更为丰富的理论依据。
Non-alcoholic fatty liver disease(NAFLD)is a common type of fatty liver disease. It is classified as"accumulation""sputum""gas"and"hypochronic pain". In areas such as Chinese medicine,most scholars believe that the cause of the disease is phlegm and blood stasis. The main pathogenesis is liver dysfunction,dys-splenism,and phlegm and blood stasis binding together,the clinical diagnosis and treatment are mainly based on regulating Qi and dispelling phlegm,or promoting blood circulation and removing blood stasis,or both at the same time,complement each other,the curative effect is quite remarkable. In this paper,the research progress of non-alcoholic fatty liver in recent years is based on the theory of traditional Chinese medicine as the main entry point,in order to provide a more theoretical basis for the diagnosis and treatment of non-alcoholic fatty liver disease.
Non-alcoholic fatty liver disease(NAFLD)is a common type of fatty liver disease. It is classified as"accumulation""sputum""gas"and"hypochronic pain". In areas such as Chinese medicine,most scholars believe that the cause of the disease is phlegm and blood stasis. The main pathogenesis is liver dysfunction,dys-splenism,and phlegm and blood stasis binding together,the clinical diagnosis and treatment are mainly based on regulating Qi and dispelling phlegm,or promoting blood circulation and removing blood stasis,or both at the same time,complement each other,the curative effect is quite remarkable. In this paper,the research progress of non-alcoholic fatty liver in recent years is based on the theory of traditional Chinese medicine as the main entry point,in order to provide a more theoretical basis for the diagnosis and treatment of non-alcoholic fatty liver disease.
引文
[1]中华医学会肝脏病学分会脂肪肝和酒精性肝病学组.非酒精性脂肪性肝病诊断标准[J].实用肝脏病杂志,2007,10(1):1.
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[11]施钦柔,陈文慧,黄文俊,等.从瘀痰互结论治脂肪肝研究进展[J].广西中医学院学报,2011,14(3):61-62.
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[16]高翔.祛痰活血汤对非酒精性脂肪大鼠的干预作用[D].泸州:泸州医学院,2012
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[18]徐朝阳,叶放.周仲英教授从痰湿瘀滞论治非酒精性脂肪性肝病经验[J].中国现代医生,2012,50(36):81-82.
[19]徐睿熙.衡先培从痰瘀论治非酒精性脂肪肝的经验[J].广西中医药,2016,39(2):62-64.
[20]黄静娟.活血与化痰基础方治疗非酒精性脂肪肝的实验研究[D].北京:首都医科大学,2007.
[21]曲万利.辨证治疗非酒精性脂肪肝65例[J].河南中医,2012,32(7):843.
[22]代三红.中医辨证治疗非酒精性脂肪肝516例[J].陕西中医,2011,32(11):1478-1480.
[23]盛庆寿,农慧,吴发胜,等.枳实消痞丸治疗脾虚气滞型非酒精性脂肪肝疗效观察[J].辽宁中医杂志,2013,40(5):932-934.
[24]胡子毅,叶菁.蒋小敏教授辨治非酒精性脂肪肝经验[J].河北中医,2015,37(12):1768-1771.
[25]刘海燕.加味涤痰汤治疗非酒精性脂肪肝56例[J].湖北中医杂志,2014,36(2):37.
[26]周爱华.中医辨证治疗酒精性脂肪肝145例临床观察[J].中国民族民间医药,2014,23(19):70-71.
[27]郑佳连.自拟活血祛湿方治疗非酒精性脂肪性肝炎临床和实验研究[D].沈阳:辽宁中医药大学,2016.
[28]戚国勇,徐海虹,童林根.益气化痰活血汤治疗非酒精性脂肪性肝病32例[J].中西医结合肝病杂志,2010,20(4):247-248.
[29]王凌云.化痰祛瘀法治疗非酒精性脂肪肝临床观察[J].湖北中医杂志,2015,37(6):34-35.
[30]姜德民,王一强,张玉香.非酒精性脂肪肝的中医药研究进展[J].西部中医药,2016,29(6):160-162.
[31]董宏强,赵玉清,康静.“降脂膏”贴脐治疗非酒精精性单纯性脂肪肝的疗效观察[J].中医临床研究,2014,6(1):92-93.
[32]杨化冰,李永康.穴位注射治疗脂肪肝37例临床观察[J].山东中医药大报,2013,28(6):442-443.
[33]张明慧.刺络泻血疗法治疗肝郁脾虚型非酒精性脂肪性肝病的量效研究[D].北京:北京中医药大学,2013.
[34]钱静娟,华忠,刘霞英,等.针灸治疗非酒精性脂肪肝疗效观察与护理[J].现代中西医结合杂志,2012,21(9):998-999.
[35]杨旭,黄文贞,王秋玲,等.非酒精性脂肪肝饮食疗法的研究进展[J].现代临床护理,2015,14(4):73-76.
[2]中华医学会肝病学分会脂肪肝和酒精性肝病学组.非酒精性脂肪性肝病诊疗指南(2010年修订版)[J].现代医药卫生,2011,27(3):641.
[3]张顺贞,李章龙,姚政,等.从痰瘀理论探讨非酒精性脂肪肝的治疗[J].云南中医中药杂志,2015,36(6):21-23.
[4]孟胜喜,冯琴,胡义扬,等.从痰瘀角度论治非酒精性脂肪性肝病[J].中华中医药杂志,2013,28(6):623-625.
[5]张技.非酒精性脂肪肝的中医药治疗研究进展[J].中药与临床,2014,5(1):63.
[6]胡义扬.加强脂肪肝的中医药治疗研究[J].中国中西医结合杂志,2007,27(4):293-295.
[7]薛欣,李海玉,李玉梅,等.从痰论治脂肪肝机制探讨[J].中国中医基础医学杂志,2014,20(11):1472-1475.
[8]孙琳,赵安聚,魏玉成,等.从痰瘀论治非酒精性脂肪肝研究进展[J].实用医药杂志,2016,33(10):944-947.
[9]李松梅,吕花荣,蔡豪,等.中医对非酒精性脂肪肝病因病机的认识及辨证论治[J].云南中医中药杂志,2015,36(5):91-93.
[10]隋晓丹,邓厚波,刘铁军.中医对非酒精性脂肪肝病机辩证研究进展[J].中医实用医药,2013,8(26):247-248.
[11]施钦柔,陈文慧,黄文俊,等.从瘀痰互结论治脂肪肝研究进展[J].广西中医学院学报,2011,14(3):61-62.
[12]陈少东,李红山,冯琴,等.脂肪肝中医证型分类的文献分析[J].中西医结合肝病杂志,2006,16(4):651.
[13]张谷运.关茂桧辨治脂肪肝的经验[J].中西医结合肝病杂志,2003,13(2):108-109.
[14]马红学,李佩芳,皇菊莲.非酒精性脂肪肝的中西医研究进展[J].山西中医学院学报,2015,116(2):76-78.
[15]彭孟云,朱晓宁,汪静.非酒精性脂肪肝从痰瘀论治[J].中国中医药现代远程教育,2016,14(22):53-55.
[16]高翔.祛痰活血汤对非酒精性脂肪大鼠的干预作用[D].泸州:泸州医学院,2012
[17]陈文慧,张超.去脂软肝汤治疗脂肪肝126例疗效观察[J].云南中医中药杂志,2000,21(5):1.
[18]徐朝阳,叶放.周仲英教授从痰湿瘀滞论治非酒精性脂肪性肝病经验[J].中国现代医生,2012,50(36):81-82.
[19]徐睿熙.衡先培从痰瘀论治非酒精性脂肪肝的经验[J].广西中医药,2016,39(2):62-64.
[20]黄静娟.活血与化痰基础方治疗非酒精性脂肪肝的实验研究[D].北京:首都医科大学,2007.
[21]曲万利.辨证治疗非酒精性脂肪肝65例[J].河南中医,2012,32(7):843.
[22]代三红.中医辨证治疗非酒精性脂肪肝516例[J].陕西中医,2011,32(11):1478-1480.
[23]盛庆寿,农慧,吴发胜,等.枳实消痞丸治疗脾虚气滞型非酒精性脂肪肝疗效观察[J].辽宁中医杂志,2013,40(5):932-934.
[24]胡子毅,叶菁.蒋小敏教授辨治非酒精性脂肪肝经验[J].河北中医,2015,37(12):1768-1771.
[25]刘海燕.加味涤痰汤治疗非酒精性脂肪肝56例[J].湖北中医杂志,2014,36(2):37.
[26]周爱华.中医辨证治疗酒精性脂肪肝145例临床观察[J].中国民族民间医药,2014,23(19):70-71.
[27]郑佳连.自拟活血祛湿方治疗非酒精性脂肪性肝炎临床和实验研究[D].沈阳:辽宁中医药大学,2016.
[28]戚国勇,徐海虹,童林根.益气化痰活血汤治疗非酒精性脂肪性肝病32例[J].中西医结合肝病杂志,2010,20(4):247-248.
[29]王凌云.化痰祛瘀法治疗非酒精性脂肪肝临床观察[J].湖北中医杂志,2015,37(6):34-35.
[30]姜德民,王一强,张玉香.非酒精性脂肪肝的中医药研究进展[J].西部中医药,2016,29(6):160-162.
[31]董宏强,赵玉清,康静.“降脂膏”贴脐治疗非酒精精性单纯性脂肪肝的疗效观察[J].中医临床研究,2014,6(1):92-93.
[32]杨化冰,李永康.穴位注射治疗脂肪肝37例临床观察[J].山东中医药大报,2013,28(6):442-443.
[33]张明慧.刺络泻血疗法治疗肝郁脾虚型非酒精性脂肪性肝病的量效研究[D].北京:北京中医药大学,2013.
[34]钱静娟,华忠,刘霞英,等.针灸治疗非酒精性脂肪肝疗效观察与护理[J].现代中西医结合杂志,2012,21(9):998-999.
[35]杨旭,黄文贞,王秋玲,等.非酒精性脂肪肝饮食疗法的研究进展[J].现代临床护理,2015,14(4):73-76.