摘要
目的研究神经外科住院患者医院感染的危险因素,为降低医院感染提供科学依据。方法通过回顾性分析方法,选取某医院神经外科住院患者进行医院感染危险因素分析。结果该医院神经外科2014-2016年共收治住院患者6 300例,发生医院感染564例,感染率为8. 95%。医院感染部位前3位为下呼吸道、器官腔隙和泌尿道感染,分别占50. 56%、30. 34%和9. 79%。神经外科住院患者医院感染标本分离出的病原菌居前3位的是鲍曼不动杆菌、凝固酶阴性葡萄球菌和铜绿假单胞菌,分别占42. 35%、33. 33%和7. 44%。多因素分析发现,患者合并基础疾病、手术类型、手术时长、侵入性操作、抗菌药物使用及住院天数是构成医院感染的独立危险因素(P <0. 05)。结论导致神经外科患者发生感染有多种危险因素,应制定针对性的防控措施,以降低神经外科医院感染率。
Objective To study the risk factors of nosocomial infection in neurosurgical inpatients and to provide scientific basis for reducing nosocomial infection. Methods By retrospective analysis,the risk factors of nosocomial infection were analyzed among neurosurgical inpatients in a hospital. Results A total of 6 300 inpatients were admitted to the department of neurosurgery in the hospital from 2014 to 2016,and 564 cases of nosocomial infection occurred,with an infection rate of8. 95%. The top three sites of nosocomial infection were the lower respiratory tract,organ lacunae and urinary tract infection,accounting for 50. 56%,30. 34% and 9. 79% respectively. The top three pathogens isolated from the specimens of patients with nosocomial infection were Acinetobacter baumannii,coagulase-negative Staphylococcus and Pseudomonas aeruginosa,which accounted for 42. 35%,33. 33% and 7. 44% respectively. Multivariate analysis showed that patients with underlying diseases,type of operation,duration of operation,invasive operation,use of antibiotics and length of hospital stay were independent risk factors for nosocomial infection( P < 0. 05). Conclusion There are many risk factors leading to infection in neurosurgery patients. Targeted prevention and control measures should be developed to reduce the nosocomial infection rate in patients of neurosurgery.
引文
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