Effect of intensive insulin therapy on β-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial
- 作者：Jianping Weng ; Yanbing Li ; Wen Xu ; Lixin Shi ; Qiao Zhang ; Dalong Zhu ; Yun Hu ; Zhiguang Zhou ; Xiang Yan ; Haoming Tian ; Xingwu Ran ; Zuojie Luo ; Jing Xian ; Li Yan ; Fangping Li ; Longyi Zeng ; Yanming Chen
- 关键词：G protein ;
//www.sciencedirect.com/scidirimg/entities/204e.gif" alt="greek small letter alpha" title="greek small letter alpha" border="0"> Subunits ; Mg2+ ; Fluorescence spectroscopy ; Furaptra
- 刊名：The Lancet
- 出版年：2008
- 期刊代码：182_01406736
- 类别：med
- 出版时间：24 May 2008-30 May 2008
- 卷：371
- 期：9626
- 页码：1753-1760
- 文件大小：160 K
摘要
Early intensive insulin therapy in patients with newly diagnosed type 2 diabetes might improve β-cell function and result in extended glycaemic remissions. We did a multicentre, randomised trial to compare the effects of transient intensive insulin therapy (continuous subcutaneous insulin infusion [CSII] or multiple daily insulin injections [MDI]) with oral hypoglycaemic agents on β-cell function and diabetes remission rate.