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Médicaments et nutrition entérale : audit sur la galénique, le pilage et le mode d'administration
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摘要
Drugs' administration via feeding tubes requires specific care because of the problems of interactions and not adapted galenic forms. We analyzed the prescriptions of patients with enteral feeding and determined if the galenics forms were compatible with enteral feeding. We also analyzed the methods of drug's passage by nurses.

Methods

In 2006 1725 patients at the hospital in Nancy were exclusively given enteral feeding. Among those patients 200 prescriptions were analysed by a prospective and exhaustive way between April and June 20O6. Twenty-nine nurses'teams were audited. The practices nurses were compared with the recommendations of the Haute Autorité de santé (HAS).

Results

Only 17%of the 671 drugs were liquids. Sixty-five percent of the drugs were pulverised or the capsule were opened. The galenic form was not in conformity for 33%of the drugs: because of the existence of a liquid, soluble or dispersible form (20%), or because of a prohibition to crushing tablet or opening of the capsule (5%). Among 101 drugs administred by 29 different teams: the administration were not inappropriate for 7%(crushing the anti-cancer drug without precaution, drugs that were dissolved while they should not have been…) The time between passage of the drug and the enteral nutrition were not respected for 11%of the drugs. The gloves were not worn in 52%of the observations and the mask in 76%. The drugs were managed in mixture for 93%of the observations. No rinsing was made after drugs administration in 27%of the cases, never between consecutive administrations and seldom before administration.

Conclusion

This study shows: 1) that it is possible to facilitate the administration of the drugs by prescribing liquid forms, soluble or dispersibles (possible for 57%of the treatments but was used only in 34%of the drugs); 2) it puts forward the lack of protocols of administration and the need for a cooperation with the pharmacists in order to control and to adapt the galenic forms.

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