Coagulation abnormalities in deceased donors are associated with unsuccessful human islet cell isolation

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• 作者：Jong Man Kim^a ; Sang Man Jin^b ; Seung Hoon Oh^c ; Han-Sin Lee^d ; Jae Hyeon Kim^b ; ^{jaehyeonmd.kim@samsung.com} ; Choon Hyuck David Kwon^a ; Sung Joo Kim^a ; ^{kmhyj111@skku.edu} ; Jae-Won Joh^a ; Kwang Won Kim^b
• 关键词：International normalized ratio (INR) ; Coagulation ; Inflammation ; Islet isolation
• 刊名：Diabetes Research and Clinical Practice
• 出版年：2012
• 期刊代码：78_01688227
• 类别：med
• 出版时间：March, 2012
• 卷：95
• 期：3
• 页码：e45-e48
• 文件大小：228 K

摘要

An equivalent islet number (EIN) greater than 300,000 is necessary for islet cell transplantation for a recipient who weighs about 60 kg. The aim of this study is to identify factors that affect isolation outcome. The most significant independent predictor for successful islet isolation from deceased donors was low international normalized ratio (INR).