• 作者：Clara Jimé ; nez-Rubio ; ^{june11580@hotmail.com} ; Ricardo Vivancos-Delgado ; Beatriz Pé ; rez-Villardó ; n ; Ana Marí ; a Garcí ; a-Belló ; n ; Ana Marí ; a Gonzá ; lez-Gonzá ; lez ; José ; Luis Delgado-Prieto ; Joaquí ; n Cano-Nieto ; José ; Marí ; a Sá ; nchez Calle ; Manuel De Mora-Martí ; n
• 关键词：Pró ; tesis valvular ; Trombosis ; Cirugí ; a ; Fibrinó ; lisis
• 刊名：Cardiocore
• 出版年：2011
• 期刊代码：pca84_1889898X
• 类别：med
• 出版时间：October-December 2011
• 卷：46
• 期：4
• 页码：e51-e55
• 文件大小：269 K

Large prosthetic thrombosis, thrombus >5 mm or >0.8 cm², is associated with high morbidity and mortality. We present a series of 9 cases of large non-obstructive prosthetic thrombosis in the mitral position. The initial treatment was anticoagulation therapy in 4 patients, fibrinolysis in 3 and surgery in 2. Surgery was required as the definitive treatment in 8 of the 9 patients (89%). The mean time to surgery was 6.7 days from hospital admission and 70.2 days for patients who were readmitted, with a mean increase in the Euroscore of 9.05%and a surgery success rate of 63%. Total early mortality was 33%, reaching 55%during follow-up. Surgery is probably the most effective treatment for large prosthetic mitral valve thrombosis, and delay in therapeutic decision-making implies an increase in mortality. Optimal anticoagulant and fibrinolytic therapy are often not definitive and not without complications.