Cortical thickness of the frontopolar area in typically developing children and adolescents

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• 作者：O'Donnell ; Shannon ; Noseworthy ; Michael D. ; Levine ; Brian ; Dennis ; Maureen
• 关键词：Frontopolar cortex (FPC) ; Cortical thickness ; Development ; Laterality ; Gender
• 刊名：Neuroimage
• 出版年：2005
• 期刊代码：83_10538119
• 类别：neu
• 出版时间：February 15, 2005
• 卷：24
• 期：4
• 页码：948-954
• 文件大小：521 K

摘要

The development of the frontopolar cortex (FPC) through late childhood and adolescence was investigated using measures of cortical thickness. T₁-weighted structural MRIs from 35 typically developing participants aged 8芒芒芒20 years were used to construct 3D models of the brain, from which cortical thickness was measured. There was a significant inverse association between age and cortical thickness, such that cortical thickness decreased as age increased between 8 and 20 years. There was no effect of laterality or gender on cortical thickness.