Serum cholinesterase: a potential assistant biomarker for hand, foot, and mouth disease caused by enterovirus 71 infection
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- 作者：Bang-Ning Cheng ; Yu-Lian Jin ; Bi-Quan Chen ; Li-Yan Zhu…
- 关键词：Serum cholinesterase ; Hand ; foot ; and mouth disease ; Enterovirus 71 ; Coxsackievirus A16 ; Children ; Biochemical marker
- 刊名：Infectious Diseases of Poverty
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：5
- 期：1
- 全文大小：918 KB
- 刊物主题：Infectious Diseases; Tropical Medicine;
- 出版者：BioMed Central
- ISSN：2049-9957
文摘
Background Hand, foot, and mouth disease (HFMD) caused by enterovirus 71 (EV71) is a potentially life-threatening infectious disease that commonly occurs in children. Diagnosis of HFMD caused by EV71 largely depends on clinical manifestations and rare serological biomarkers used to identify children suffering from HFMD. Serum cholinesterase (SChE) activity has frequently been reported as a potential biomarker for solid central nervous system tumors, chronic heart failure, and liver cirrhosis. However, its potential value in the diagnosis of neurotropic virus infections, such as HFMD caused by EV71, remains to be determined.