MicroRNA-32 promotes cell proliferation, migration and suppresses apoptosis in breast cancer cells by targeting FBXW7
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- 作者：Wei Xia ; JueYu Zhou ; HaiBo Luo ; YunZhou Liu ; CanCan Peng…
- 关键词：MiR ; 32 ; Breast cancer ; FBXW7 ; Proliferation ; Apoptosis
- 刊名：Cancer Cell International
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：17
- 期：1
- 全文大小：3703KB
- 刊物主题：Cancer Research; Cell Biology;
- 出版者：BioMed Central
- ISSN：1475-2867
- 卷排序：17
文摘
BackgroundMicroRNAs are a class of small non-coding RNAs that are involved in many important physiological and pathological processes by regulating gene expression negatively. The purpose of this study was to investigate the effect of miR-32 on cell proliferation, migration and apoptosis and to determine the functional connection between miR-32 and FBXW7 in breast cancer.