GAD vaccine reduces insulin loss in recently diagnosed type 1 diabetes: findings from a Bayesian meta-analysis

详细信息    查看全文

• 作者：Craig A. Beam ; Colleen MacCallum ; Kevan C. Herold ; Diane K. Wherrett…
• 关键词：Bayes methods ; Glutamic acid decarboxylase (GAD) ; Meta ; analysis ; Type 1 diabetes ; Vaccine
• 刊名：Diabetologia
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：60
• 期：1
• 页码：43-49
• 全文大小：
• 刊物类别：Medicine
• 刊物主题：Internal Medicine; Metabolic Diseases; Human Physiology;
• 出版者：Springer Berlin Heidelberg
• ISSN：1432-0428
• 卷排序：60

文摘

Aims/hypothesisGAD is a major target of the autoimmune response that occurs in type 1 diabetes mellitus. Randomised controlled clinical trials of a GAD + alum vaccine in human participants have so far given conflicting results.