Single-Molecule Force Spectroscopy Quantification of Adhesive Forces in Cucurbit[8]Uril Host–Guest Ternary Complexes
详细信息 查看全文
- 作者：Zarah Walsh-KorbYing Yu ; Emma-Rose Janeček ; Yang Lan ; Jesús del Barrio ; Paul E. WilliamsXi Zhang ; Oren A. Scherman
- 刊名：Langmuir
- 出版年：2017
- 出版时间：February 14, 2017
- 年：2017
- 卷：33
- 期：6
- 页码：1343-1350
- 全文大小：429K
- ISSN：1520-5827
文摘
Cucurbit[8]uril (CB[8]) heteroternary complexes display certain characteristics making them well-suited for molecular level adhesives. In particular, careful choice of host–guest binding pairs enables specific, fully reversible adhesion. Understanding the effect of the environment is also critical when developing new molecular level adhesives. Here we explore the binding forces involved in the methyl viologen·CB[8]·naphthol heteroternary complex using single-molecule force spectroscopy (SMFS) under a variety of conditions. From SMFS, the interaction of a single ternary complex was found to be in the region of 140 pN. Additionally, a number of surface interactions could be readily differentiated using the SMFS technique allowing for a deeper understanding of the dynamic heteroternary CB[8] system on the single-molecule scale.