文摘
A series of new N-halamine epoxide precursors, 3-glycidyl-5,5-dialkylhydantoins (GH's), has been synthesizedby a very facile and economic method. Cellulose surfaces can be treated with GH's and rendered biocidal byexposure to halogen solutions after curing the treated material. The biocidal efficacy tests showed that thechlorinated treated cellulose surfaces were antimicrobial with contact times required for 6-7 log reductionsof Staphylococcus aureus and Escherichia coli O157:H7 of 5-30 min. It was found in simulated washingtests that celluloses, such as cotton swatches, treated with 3-glycidyl-5,5-dimethylhydantoin were quite stableand could survive more than the equivalent of 50 repeated home launderings with very little loss. Upon lossof the biocidal property due to long-term use, the treated surfaces could be recharged by further exposure todilute bleach to regain antimicrobial activity. In addition, since only water was used as a solvent for thesynthesis of GH's at room temperature, the reaction solution could be directly used as a treatment solution.Stability tests showed that the reaction solutions were relatively stable at room temperature and more stableat 5 C over a period of at least 30 d. Preliminary experiments have shown that polyester swatches can alsobe treated with GH's and be rendered biocidal upon treatment with household bleach. The entire processshould be economical for commercial application.