Tandem Cyclization of 伪-Cyano 伪-Alkynyl Aryl Ketones Induced by tert-Butyl Hydroperoxide and Tetrabutylammonium Iodide

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• 作者：Ying-Chieh Wong ; Chen-Tso Tseng ; Tzu-Ting Kao ; Yu-Cheng Yeh ; Kak-Shan Shia
• 刊名：Organic Letters
• 出版年：2012
• 出版时间：December 7, 2012
• 年：2012
• 卷：14
• 期：23
• 页码：6024-6027
• 全文大小：279K
• 年卷期：v.14,no.23(December 7, 2012)
• ISSN：1523-7052

文摘

The radical cascade protocol of the 伪-cyano 伪-TMS/aryl-capped alkynyl aryl ketones promoted by tert-butyl hydroperoxide under catalysis with tetrabutylammonium iodide in refluxing benzene has been developed, leading to the construction of a variety of highly functionalized [6,6,5] tricyclic frameworks in an efficient manner.