Transcription Regulation System Mediated by Mechanical Operation of a DNA Nanostructure
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- 作者：Masayuki Endo ; Ryoji Miyazaki ; Tomoko Emura ; Kumi Hidaka ; Hiroshi Sugiyama
- 刊名：The Journal of the American Chemical Society
- 出版年：2012
- 出版时间：February 15, 2012
- 年：2012
- 卷：134
- 期：6
- 页码：2852-2855
- 全文大小：273K
- 年卷期：v.134,no.6(February 15, 2012)
- ISSN：1520-5126
文摘
A transcription regulation system initiated by DNA nanostructure changes was designed and constructed. Using the toehold system, specific DNA strands induced the opening of the tubular structure. A transcription product from the purified tube-attached dsDNA template was observed by addition of DNA strands that were specific for opening the tubular structure.