Serum Dioxin Levels in Vietnamese Men more than 40 Years after Herbicide Spraying

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• 作者：Ho Dung Manh ; Teruhiko Kido ; Rie Okamoto ; Sun XianLiang ; Le Thai Anh ; Supratman Supratman ; Shoko Maruzeni ; Muneko Nishijo ; Hideaki Nakagawa ; Seijiro Honma ; Takeshi Nakano ; Takumi Takasuga ; Dang Duc Nhu ; Nguyen Ngoc Hung ; Le Ke Son
• 刊名：Environmental Science & Technology
• 出版年：2014
• 出版时间：March 18, 2014
• 年：2014
• 卷：48
• 期：6
• 页码：3496-3503
• 全文大小：254K
• 年卷期：v.48,no.6(March 18, 2014)
• ISSN：1520-5851

文摘

Recent studies have found elevated dioxin levels inside some U.S. military former air bases in Vietnam, known as hotspots. Many studies of Agent Orange have been done in U.S. veterans; however, there is little known about Vietnamese men. In 2010, we collected blood samples from 97 men in a hotspot and 85 men in an unsprayed area in Northern Vietnam. Serum concentrations of not only TCDD but also other dioxins (PCDDs), furans (PCDFs), and nonortho polychlorinated biphenyls (PCBs) were significantly higher in the hotspot than in the unsprayed area. In the hotspot, three subareas were demarcated, based on their proximity to the air base. The total toxic equivalents (TEQ) of PCDDs/PCDFs+PCBs was 41.7 pg/g lipid in the area closest to the air base, while it was around 29 pg/g lipid in the other two subareas. In the unsprayed area, the dioxin levels were no different between men who went to the South during the Vietnam War and those who remained in the North, with TEQs PCDDs/PCDFs+PCBs of around 13.6 pg/g lipid. Our findings suggested that people living close to the former U.S. air bases might have been exposed to both Agent Orange and other sources of dioxin-like compounds.