Sub-Picomolar Recognition of Cr3+ through Bioinspired Organic–Inorganic Ensemble Utilization

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• 作者：Gourab Dey ; Mangili Venkateswarulu ; Venkateswaran Vivekananthan ; Avijit Pramanik ; Venkata Krishnan ; Rik Rani Koner
• 刊名：ACS Sensor
• 出版年：2016
• 出版时间：June 24, 2016
• 年：2016
• 卷：1
• 期：6
• 页码：663-669
• 全文大小：606K
• ISSN：2379-3694

文摘

The work describes an integrated optical platform for recognition of Cr³⁺ at the picomolar level (0.66 pM). The condensation of a fluorene unit with l-leucine led to the development of a highly fluorescent molecular probe L which detects Cu²⁺ following a turn-off signaling mechanism. Further, the L-Cu²⁺ ensemble has been successfully utilized as a light-up signaling tool for selective turn-on sensing of Cr³⁺, for the first time, at the picomolar level through quencher displacement. This sensing process eventually detects selectively one paramagnetic cation through turn-on signaling by the displacement of another paramagnetic cation. We have successfully shown that the common sensitivity issues associated with displacement approaches can be overcome by suitable ligand design. The present integrated system, L-Cu²⁺, has been found to be sensitive enough to detect Cr³⁺ at the picomolar level even in real samples, including water from different sources such as tap water, river water, and drinking water.