Rhodium(III)-Catalyzed Directed ortho-C鈥揌 Bond Functionalization of Aromatic Ketazines via C鈥揝 and C鈥揅 Coupling

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• 作者：Jing Wen ; An Wu ; Mingyang Wang ; Jin Zhu
• 刊名：Journal of Organic Chemistry
• 出版年：2015
• 出版时间：November 6, 2015
• 年：2015
• 卷：80
• 期：21
• 页码：10457-10463
• 全文大小：460K
• ISSN：1520-6904

文摘

Described herein is a convenient and efficient method for sulfuration and olefination of aromatic ketazines via rhodium-catalyzed oxidative C鈥揌 bond activation. A range of substituted substrates are supported, and a possible mechanism is proposed according to experimental results of kinetic isotopic effect, reversibility studies, and catalysis of rhodacycle intermediate c1.