Catalytic Transformation of Aldehydes with Nickel Complexes through 畏2 Coordination and Oxidative Cyclization

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• 作者：Yoichi Hoshimoto ; Masato Ohashi ; Sensuke Ogoshi
• 刊名：Accounts of Chemical Research
• 出版年：2015
• 出版时间：June 16, 2015
• 年：2015
• 卷：48
• 期：6
• 页码：1746-1755
• 全文大小：555K
• ISSN：1520-4898

文摘

Chemists no longer doubt the importance of a methodology that could activate and utilize aldehydes in organic syntheses since many products prepared from them support our daily life. Tremendous effort has been devoted to the development of these methods using main-group elements and transition metals. Thus, many organic chemists have used an activator鈥?aldehyde oxygen) interaction, namely, 畏¹ coordination, whereby a Lewis or Br酶nsted acid activates an aldehyde. In the field of coordination chemistry, 畏² coordination of aldehydes to transition metals by coordination of a carbon鈥搊xygen double bond has been well-studied; this activation mode, however, is rarely found in transition-metal catalysis. In view of the distinctive reactivity of an 畏²-aldehyde complex, unprecedented reactions via this intermediate are a distinct possibility.