Penicibilaenes A and B, Sesquiterpenes with a Tricyclo[6.3.1.01,5]dodecane Skeleton from the Marine Isolate of Penicillium bilaiae MA-267
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- 作者：Ling-Hong Meng ; Xiao-Ming Li ; Yang Liu ; Bin-Gui Wang
- 刊名：Organic Letters
- 出版年：2014
- 出版时间：December 5, 2014
- 年：2014
- 卷：16
- 期：23
- 页码：6052-6055
- 全文大小：257K
- ISSN：1523-7052
文摘
Penicibilaenes A (1) and B (2), two sesquiterpenes possessing a tricyclo[6.3.1.01,5]dodecane skeleton, were characterized from Penicillium bilaiae MA-267, a fungus obtained from the rhizospheric soil of the mangrove plant Lumnitzera racemosa. The lack of some key COSY and NOESY correlations made the structure elucidation of compound 1 difficult, which was solved by a X-ray crystallographic study. Compounds 1 and 2 exhibited selective activity against the plant pathogenic fungus Colletotrichum gloeosporioides (MIC = 1.0 and 0.125 渭g/mL, respectively).