Direct C–F Bond Formation Using Photoredox Catalysis

详细信息    查看全文

• 作者：Montserrat Rueda-Becerril ; Olivier Mahé ; Myriam Drouin ; Marek B. Majewski ; Julian G. West ; Michael O. Wolf ; Glenn M. Sammis ; Jean-Fran?ois Paquin
• 刊名：Journal of the American Chemical Society
• 出版年：2014
• 出版时间：February 12, 2014
• 年：2014
• 卷：136
• 期：6
• 页码：2637-2641
• 全文大小：370K
• ISSN：1520-5126

文摘

We have developed the first example of a photoredox catalytic method for the formation of carbon鈥揻luorine (C鈥揊) bonds. The mechanism has been studied using transient absorption spectroscopy and involves a key single-electron transfer from the ³MLCT (triplet metal-to-ligand charge transfer) state of Ru(bpy)₃²⁺ to Selectfluor. Not only does this represent a new reaction for photoredox catalysis, but the mild reaction conditions and use of visible light also make it a practical improvement over previously developed UV-mediated decarboxylative fluorinations.