Efficient Visible Light Photocatalysis of [2+2] Enone Cycloadditions
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- 作者：Michael A. Ischay ; Mary E. Anzovino ; Juana Du ; Tehshik P. Yoon
- 刊名：Journal of the American Chemical Society
- 出版年：2008
- 出版时间：October 1, 2008
- 年：2008
- 卷：130
- 期：39
- 页码：12886-12887
- 全文大小：136K
- 年卷期：v.130,no.39(October 1, 2008)
- ISSN：1520-5126
文摘
We report that Ru(bipy)3Cl2 can serve as a visible light photocatalyst for [2+2] enone cycloadditions. A variety of aryl enones participate readily in the reaction, and the diastereoselectivity in the formation of the cyclobutane products is excellent. We propose a mechanism in which a photogenerated Ru(bipy)3+ complex promotes one-electron reduction of the enone substrate, which undergoes subsequent radical anion cycloaddition. The efficiency of this process is extremely high, which allows rapid, high-yielding [2+2] cyclizations to be conducted using incident sunlight as the only source of irradiation.