Ruthenium-Catalyzed Intermolecular Direct Silylation of Unreactive C(sp3)–H Bonds

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• 作者：Wei Li ; Xiaolei Huang ; Jingsong You
• 刊名：Organic Letters
• 出版年：2016
• 出版时间：February 19, 2016
• 年：2016
• 卷：18
• 期：4
• 页码：666-668
• 全文大小：308K
• ISSN：1523-7052

文摘

A Ru-catalyzed intermolecular silylation of unreactive, aliphatic C(sp³)–H bonds has been described for the first time. This protocol features low catalyst loading, a relatively broad substrate spectrum, good functional group tolerance, and no sensitivity to air, which provides a convenient and practical pathway for the construction of C–Si bonds.