Total Synthesis and Determination of the Absolute Configuration of Vinylamycin

详细信息    查看全文

• 作者：Zhantao Yang ; Guang Yang ; Meiyan Ma ; Jiangnan Li ; Jianwei Liu ; Jinghan Wang ; Shende Jiang ; Quan Zhang ; Yue Chen
• 刊名：Organic Letters
• 出版年：2015
• 出版时间：December 4, 2015
• 年：2015
• 卷：17
• 期：23
• 页码：5725-5727
• 全文大小：268K
• ISSN：1523-7052

文摘

The absolute configurations of the three unknown chiral centers in vinylamycin were predicted according to the structural comparison with microtermolide A and rakicidin A, and then total syntheses of vinylamycin were applied to determine the three unknown chiral centers as 14R, 15R, and 16S.