Borylation of Olefin C–H Bond via Aryl to Vinyl Palladium 1,4-Migration

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• 作者：Tian-Jiao Hu ; Ge Zhang ; Ya-Heng Chen ; Chen-Guo Feng ; Guo-Qiang Lin
• 刊名：Journal of the American Chemical Society
• 出版年：2016
• 出版时间：March 9, 2016
• 年：2016
• 卷：138
• 期：9
• 页码：2897-2900
• 全文大小：411K
• ISSN：1520-5126

文摘

The aryl to vinyl palladium 1,4-migration was realized for the first time. The generated alkenyl palladium species was trapped by diboron reagents under Miyaura borylation conditions, providing a new method to synthesize β,β-disubstituted vinylboronates. The excellent regioselectivity and broad substrate scope were observed for this novel transformation.