Xylarenones C鈭扙 from an Endophytic Fungus Isolated from Alibertia macrophylla
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- 作者：Camila Martins de Oliveira ; Geraldo Humberto Silva ; Luis Octa虂vio Regasini ; Ota虂vio Flausino ; Jr. ; Silvia Noeli虂 Lo虂pez ; Ba虂rbara Marcondes Abissi ; Roberto Gomes de Souza Berlinck ; Lara Dura虄es Sette ; Rafaella Costa Bonugli-Santos ; Andre虂 Rodrigues ; Vanderlan da Silva Bolzani ; Angela Regina Araujo
- 刊名：Journal of Natural Products
- 出版年：2011
- 出版时间：June 24, 2011
- 年：2011
- 卷：74
- 期：6
- 页码：1353-1357
- 全文大小：726K
- 年卷期：v.74,no.6(June 24, 2011)
- ISSN：1520-6025
文摘
Xylarenones C鈭扙 (2鈭?b>4), three new eremophilane sesquiterpenes, have been isolated from solid substrate cultures of a Camarops-like endophytic fungus isolated from Alibertia macrophylla. The structures were elucidated by analysis of spectroscopic data. Compounds were evaluated in subtilisin and pepsin protease assays, and compound 2 showed potent inhibitory activity against both proteases.