Efficient NiII2LnIII2 Electrocyclization Catalysts for the Synthesis of trans-4,5-Diaminocyclopent-2-enones from 2-Furaldehyde and Primary or Secondary Amines

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• 作者：Kieran Griffiths ; Prashant Kumar ; James D. Mattock ; Alaa Abdul-Sada ; Mateusz B. Pitak ; Simon J. Coles ; Oscar Navarro ; Alfredo Vargas ; George E. Kostakis
• 刊名：Inorganic Chemistry
• 出版年：2016
• 出版时间：July 18, 2016
• 年：2016
• 卷：55
• 期：14
• 页码：6988-6994
• 全文大小：442K
• 年卷期：0
• ISSN：1520-510X

文摘

A series of heterometallic coordination clusters (CCs) [Nip>IIp>₂Lnp>IIIp>₂(L1)₄Cl₂(CH₃CN)₂] 2CH₃CN [Ln = Y (1Y), Sm (1Sm), Eu (1Eu), Gd (1Gd), or Tb (1Tb)] were synthesized by the reaction of (E)-2-(2-hydroxy-3-methoxybenzylidene-amino)phenol) (H₂L1) with NiCl₂·6(H₂O) and LnCl₃·x(H₂O) in the presence of Et₃N at room temperature. These air-stable CCs can be obtained in very high yields from commercially available materials and are efficient catalysts for the room-temperature domino ring-opening electrocyclization synthesis of trans-4,5-diaminocyclopent-2-enones from 2-furaldehyde and primary or secondary amines under a non-inert atmosphere. Structural modification of the catalyst to achieve immobilization or photosensitivity is possible without deterioration in catalytic activity.