Stereoselective Synthesis of Novel Highly Substituted Isochromanone and Isoquinolinone-Containing Exocyclic Tetrasubstituted Alkenes

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• 作者：Martin Arthuis ; Rene Pontikis* ; Jean-Claude Florent*
• 刊名：Journal of Organic Chemistry
• 出版年：2009
• 出版时间：March 6, 2009
• 年：2009
• 卷：74
• 期：5
• 页码：2234-2237
• 全文大小：183K
• 年卷期：v.74,no.5(March 6, 2009)
• ISSN：1520-6904

文摘

An efficient synthetic route toward the synthesis of highly substituted arylethylidene−isoquinolinones/isochromanones is reported. The tandem carbopalladation/Suzuki−Miyaura coupling sequence stereoselectively provided various functionalized polycyclic compounds in moderate to excellent yields.