Ti-Catalyzed Reformatsky-Type Coupling between -Halo Ketones and Aldehydes
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- 作者：Rosa E. Esté ; vez ; Miguel Paradas ; Alba Millá ; n ; Tania Jimé ; nez ; Rafael Robles ; Juan M. Cuerva ; J. Enrique Oltra
- 刊名：Journal of Organic Chemistry
- 出版年：2008
- 出版时间：February 15, 2008
- 年：2008
- 卷：73
- 期：4
- 页码：1616 - 1619
- 全文大小：75K
- 年卷期：v.73,no.4(February 15, 2008)
- ISSN：1520-6904
文摘
-halo ketones and aldehydes. The reaction affords
-hydroxy ketones under mild, neutral conditions compatiblewith ketones and other electrophiles. The catalytic cyclepossibly proceeds via bis(cyclopentadienyl)titanium enolates.