Biosensor Based on Degree of Coherence of A Pair of Surface Plasma Waves

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• 作者：Chien Chou ; Chien-Wa Ho ; Sheng-Yi Chang ; Nai-Chuan Chen ; Ying-Feng Chang ; Li-Chen Su ; Cheng-Chung Lee
• 刊名：The Journal of Physical Chemistry C
• 出版年：2012
• 出版时间：November 29, 2012
• 年：2012
• 卷：116
• 期：47
• 页码：25022-25027
• 全文大小：309K
• 年卷期：v.116,no.47(November 29, 2012)
• ISSN：1932-7455

文摘

A novel 鈥渄egree of coherence paired surface plasma wave biosensor鈥?(DOC-PSPWB) is proposed wherein the principle of detection involves the degree of coherence of highly correlated surface plasma waves when these are excited on a metal/dielectric interface within the DOC-PSPWB. Using the sensor, the concentration of total PSA (t-PSA) in a phosphate-buffered saline solution was measured, and a detection limit of 0.015pg/mL was determined experimentally. Finally, the dynamic range of the DOC-PSPWB when used on samples with ultralow molecular concentrations is discussed.