Customizable Optical and Biofunctional Properties of a Medical Lens Based on Chemical Vapor Deposition Encapsulation of Liquids

详细信息    查看全文

• 作者：Jyun-Ting Wu ; Chih-Yu Wu ; Shih-Kang Fan ; Chih-Chen Hsieh ; Yu-Chih Hou ; Hsien-Yeh Chen
• 刊名：Chemistry of Materials
• 出版年：2015
• 出版时间：October 27, 2015
• 年：2015
• 卷：27
• 期：20
• 页码：7028-7033
• 全文大小：311K
• ISSN：1520-5002

文摘

An innovative intraocular lens (IOL) device was fabricated based on a chemical vapor deposition encapsulation process using functionalized poly-p-xylylenes. The advanced IOL device provides noncompromised design parameters for both its optical and biological properties. As an excellent optical device, it provides a high refractive index and a tunable effective focal length that is realized by manipulating the wetting properties of the encapsulated liquids; the device also offers protection from UV radiation. As a key medical device, it exhibits excellent biocompatibility and reduced postoperative calcification through the intrinsic properties of poly-p-xylylenes. In addition, these synergic functions are provided with precise surface chemistry for location to a guided attachment or repellent properties for eye epithelial cells, which is important in preventing device-associated complications.