Near-Infrared Fluorescence Imaging with Water-Soluble Lead Salt Quantum Dots

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• 作者：Byung-Ryool Hyun ; Hongyu Chen ; Diego A. Rey ; Frank W. Wise ; Carl A. Batt
• 刊名：Journal of Physical Chemistry B
• 出版年：2007
• 出版时间：May 24, 2007
• 年：2007
• 卷：111
• 期：20
• 页码：5726 - 5730
• 全文大小：2083K
• 年卷期：v.111,no.20(May 24, 2007)
• ISSN：1520-5207

文摘

A simple procedure for transferring PbS and PbSe quantum dots into water is presented, along withcharacterization of the resulting water-soluble quantum dots. The external surface of the water-soluble quantumdots include carboxylic groups, which will allow target-specific labeling of cells. As a first example, near-infrared fluorescence imaging of human colon cancer cells is demonstrated using these water-soluble near-infrared fluorophores.