Palladium-Catalyzed Synthesis of 2-Aryl-2H-Benzotriazoles from Azoarenes and TMSN3

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• 作者：Nilufa Khatun ; Anju Modi ; Wajid Ali ; Bhisma K. Patel
• 刊名：Journal of Organic Chemistry
• 出版年：2015
• 出版时间：October 2, 2015
• 年：2015
• 卷：80
• 期：19
• 页码：9662-9670
• 全文大小：643K
• ISSN：1520-6904

文摘

Substrate-directed ortho C鈥揌 amination of azoarenes using TMSN₃ as the source of nitrogen leading to the synthesis of 2-aryl-2H-benzotriazoles has been accomplished with the help of Pd/TBHP combinations. An intermolecular o-azidation (C鈥揘 bond formation) followed by an intramolecular N鈥揘 bond formation via nucleophilic attack of one of the azo nitrogen onto the o-azide nitrogen leads to cyclization with the expulsion of N₂.