Human Saliva Forms a Complex Film Structure on Alumina Surfaces
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- 作者：Marité ; Cá ; rdenas ; Thomas Arnebrant ; Adrian Rennie ; Giovanna Fragneto ; Robert K. Thomas ; Liselott Lindh
- 刊名：Biomacromolecules
- 出版年：2007
- 出版时间：January 2007
- 年：2007
- 卷：8
- 期：1
- 页码：65 - 69
- 全文大小：209K
- 年卷期：v.8,no.1(January 2007)
- ISSN：1526-4602
文摘
Films formed from saliva on surfaces are important for the maintenance of oral health and integrity by protectionagainst chemical and/or biological agents. The aim of the present study was to investigate adsorbed amounts,thickness, and structure of films formed from human whole saliva on alumina surfaces by means of in situellipsometry, neutron reflectivity, and atomic force microscopy. Alumina (Al2O3, synthetic sapphire) is a relevantand interesting substrate for saliva adsorption studies as it has an isoelectric point close to that of tooth enamel.The results showed that saliva adsorbs rapidly on alumina. The film could be modeled in two layers: an innerand dense thin region that forms a uniform layer and an outer, more diffuse and thicker region that protrudestoward the bulk of the solution. The film morphology described a uniformly covering dense layer and a secondouter layer containing polydisperse adsorbed macromolecules or aggregates.