Therapeutic hyperthermia: The old, the new, and the upcoming
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- 作者：Matthew Mallory<sup>asup><sup> ; sup><sup>mlm3xe@virginia.edu" class="auth_mail" title="E-mail the corresponding authorsup>Author Vitae ; Emile Gogineni<sup>bsup><sup> ; sup><sup>gogie42@gmail.com" class="auth_mail" title="E-mail the corresponding authorsup> ; Guy C. Jones<sup>csup><sup> ; sup><sup>guy.jones@nih.gov" class="auth_mail" title="E-mail the corresponding authorsup>Author Vitae ; Lester Greer<sup>dsup><sup> ; sup><sup>Lester.l.greer.mil@health.mil" class="auth_mail" title="E-mail the corresponding authorsup> ; Charles B. Simone II<sup>esup><sup> ; sup><sup>charles.simone@uphs.upenn.edu" class="auth_mail" title="E-mail the corresponding authorsup>Author Vitae
- 关键词：EBRT ; external beam radiation therapy ; HT ; hyperthermia ; EIA ; etoposide ; ifosfamide ; and doxorubicin ; pCR ; pathologic complete response rate ; MMC ; mitomycin C
- 刊名：Critical Reviews in Oncology and Hematology
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：97
- 期：Complete
- 页码：56-64
- 全文大小：719 K
文摘
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Hyperthermia continues to show clinical benefits in randomized trials across a spectrum of malignancies, with generally well-tolerated side effects when administered as multimodality therapy.
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Hyperthermia contributes direct tumor cell killing and may also enhance the antitumor effects of chemotherapy and radiation therapy.
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Its widespread adoption has been impeded by technological and delivery barriers that are now being addressed through new commercial solutions.
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It would serve physicians of all on cological disciplines to stay informed of new developments and consider integrating these promising techniques into their practice.