Atorvastatin enhances angiogenesis to reduce subdural hematoma in a rat model
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- 作者：Dong Wanga ; 1 ; 54454241@qq.com" class="auth_mail" title="E-mail the corresponding author ; Tuo Lia ; 1 ; lt19880619@sina.com" class="auth_mail" title="E-mail the corresponding author ; Huijie Weia ; huijiewei@126.com" class="auth_mail" title="E-mail the corresponding author ; Yi Wanga ; sinuosiwo@sina.com" class="auth_mail" title="E-mail the corresponding author ; Guili Yangb ; yangguili1985@163.com" class="auth_mail" title="E-mail the corresponding author ; Ye Tiana ; yetian1986@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Zilong Zhaoa ; ZilongZ@BloodWorksNW.org" class="auth_mail" title="E-mail the corresponding author ; Liang Wangc ; 757171007@qq.com" class="auth_mail" title="E-mail the corresponding author ; Shengping Yub ; yshpvip@sina.com" class="auth_mail" title="E-mail the corresponding author ; Yongqiang Zhangb ; friskyzyq@163.com" class="auth_mail" title="E-mail the corresponding author ; Jieli Chend ; jieli@neuro.hfh.edu" class="auth_mail" title="E-mail the corresponding author ; Rongcai Jiangb ; jiang116216@163.com" class="auth_mail" title="E-mail the corresponding author ; Jian Ning Zhanga ; jianningzhang@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Subdural hematoma ; Atorvastatin ; Angiogenesis ; Rat model
- 刊名：Journal of the Neurological Sciences
- 出版年：2016
- 出版时间：15 March 2016
- 年：2016
- 卷：362
- 期：Complete
- 页码：91-99
- 全文大小：2232 K
文摘
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Atorvastatin promotes blood absorption in a rat model of subdural hematoma.
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The effect is mediated by atorvastatin-induced angiogenesis in the hematoma wall.
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Atorvastatin at low doses promotes vascular maturation by regulating vascular factors.