Concentration of ⁶⁸Ga via solvent extraction

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• 作者：Tanveer Hussain Bokhari ; A. Mushtaq ; Islam Ullah Khan
• 关键词：⁶⁸Ge– ; ⁶⁸Ga generator ; Methyl ethyl ketone ; Solvent extraction ; Concentration of ⁶⁸Ga
• 刊名：Applied Radiation and Isotopes
• 出版年：2009
• 出版时间：January 2009
• 年：2009
• 卷：67
• 期：1
• 页码：100-102
• 全文大小：126 K

文摘

The metallic cation, ⁶⁸Ga (III) is suitable for complexation with chelators either naked or conjugated with biological macromolecules, however, such labeling procedure requires high chemical purity and concentrated solutions of ⁶⁸Ga (III), which cannot be sufficiently fulfilled by the presently available ⁶⁸Ge/⁶⁸Ga generator eluate. A method to increase the concentration and purity of ⁶⁸Ga obtained from a commercial ⁶⁸Ge/⁶⁸Ga generator has been developed. The ⁶⁸Ga eluate (1 M HCl) is extracted in methyl ethyl ketone, which is evaporated and taken in a small volume of buffer.