Immune Reconstitution after Allogeneic Hematopoietic Cell Transplantation in Children
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- 作者：Coco de Koning1 ; Maud Plantinga1 ; Paul Besseling1 ; Jaap Jan Boelens1 ; 2 ; Stefan Nierkens1 ; snierken@umcutrecht.nl" class="auth_mail" title="E-mail the corresponding author
- 关键词：Allogeneic hematopoietic cell transplantation ; Immune reconstitution ; Secretome ; Pediatric patients ; Serotherapy ; Biomarkers
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：22
- 期：2
- 页码：195-206
- 全文大小：545 K
文摘
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Complications and mortality after hematopoietic cell transplantation are strongly related to immune reconstitution.
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Current immune reconstitution data are mostly derived from routine measurements.
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Detailed information on early immune reconstitution (subsets, function) is lacking.
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Secretome biomarkers may be important (early) predictors for complications.