Transcranial Direct Current Stimulation in Mesial Temporal Lobe Epilepsy and Hippocampal Sclerosis
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- 作者：Daniel San-Juan<sup>asup><sup> ; sup><sup>bsup><sup> ; sup><sup>pegaso31@yahoo.comsup> ; Dulce Anabel Espinoza Ló ; pez<sup>asup> ; Rafael Vá ; zquez Gregorio<sup>asup> ; Carlos Trenado<sup>csup> ; Maricarmen Ferná ; ndez-Gonzá ; lez Aragó ; n<sup>asup> ; Leó ; n Morales-Quezada<sup>dsup><sup> ; sup><sup>esup> ; Axel Hernandez Ruiz<sup>fsup> ; Flavio Hernandez-Gonzá ; lez<sup>gsup> ; Alejandro Alcaraz-Guzmá ; n<sup>hsup> ; David J. Anschel<sup>isup> ; Felipe Fregni<sup>dsup>
- 关键词：Transcranial direct current stimulation (tDCS) ; Mesial temporal lobe epilepsy (MTLE) ; Hippocampal sclerosis (HS)
- 刊名：Brain Stimulation
- 出版年：2017
- 出版时间：January-February 2017
- 年：2017
- 卷：10
- 期：1
- 页码：28-35
- 全文大小：568 K
- 卷排序：10
文摘
Transcranial direct current stimulation (tDCS) has been evaluated in a limited number of pharmacoresistant epilepsy patients, but treatment parameters remain undefined. Safety and efficacy of two cathodal tDCS protocols were evaluated in patients with mesial temporal lobe epilepsy and hippocampal sclerosis (MTLE-HS). Three and five sessions decreased seizure frequency and interictal epileptiform discharges in MTLE-HS patients, compared to placebo.