Discovery and functional characterization of leptin and its receptors in Japanese quail (Coturnix japonica)
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- 作者：Dandan Wanga ; 1 ; Chunlin Xua ; 1 ; Taian Wanga ; Hong Lia ; Yanmin Lia ; Junxiao Rena ; Yadong Tiana ; b ; c ; Zhuanjian Lia ; b ; c ; Yuping Jiaoa ; d ; Xiangtao Kanga ; b ; c ; xtkang2001@263.net" class="auth_mail" title="E-mail the corresponding author ; Xiaojun Liua ; b ; c ; Xjliu2008@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：qLEP ; quail leptin ; qLEPR ; quail leptin receptor ; qLEPR-a ; qLEPR-b and qLEPR-c ; three soluble forms of qLEPR ; qLEPRl ; a long form of qLEPR ; t-qLEPR ; total qLEPR including all LEPR variants
- 刊名：General and Comparative Endocrinology
- 出版年：2016
- 出版时间：1 January 2016
- 年：2016
- 卷：225
- 期：Complete
- 页码：1-12
- 全文大小：1785 K
文摘
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LEP and four leptin receptor isoforms were obtained firstly in Japanese quail.
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qLEP and the four qLEPR isoforms were expressed extensively in all tissues examined.
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Fasting increases and refeeding decreases LEP and LEPR expressions of juvenile quail.
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LEP may actually act to inhibit food intake during fasting, at least in juvenile quail.
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qLEP and qLEPR may play important roles in regulating reproduction and energy status.